Structure of PDB 5wlc Chain SS Binding Site BS01

Receptor Information
>5wlc Chain SS (length=197) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRIQQRHDRKAAYEISRQEVSKWNDIVQQNRRADHLIFPLNKPTEHNHAS
AFTRTQDVPQTELQEKVDQVLQESNAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAANVIINEKVNKKNLKYQSSAVPFP
FENREQYERSLRMPIGQEWTSRASHQELIKPRIMTKPGQVIDPLKAP
Ligand information
>5wlc Chain L0 (length=488) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagacaagugcuugucguucguuaauggccucgucaaacgguggagaga
gucgcuaggugaucgucagaucugccuagucucuauacagcguguuuaau
ugacauggguugaugcguauugagagauacaauuugggaagaaauuccca
gaguguguuucuuuugcguuuaaccugaacagucucaucgugggcaucuu
gcgauuccauuggugagcagcgaaggauuugguggauuacuagcuaauag
caaucuauuucaaagaauucaaacuugggggaaugccuuguugaauauuc
uucaaguguaaccuccucucaaaucagcgauaucaaacguaccccgugaa
acaccgggguaucuguuugguggaaccugauuagaggaaacucaaagagu
gcuaugguauggugacggagugcgcuggucaagaguguaaaagcuuuuug
aacagagagcauuuccggcagcagagauuucagcuguu
<<<<<<<<<..>>>>>>.>>>............<<<<<<<<.<<...<<<
<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>...>>.>>>......>
>>>>..<<<<<<..<<<<<..<<<<<<<<<<.<<<<<<<<....>>>>>>
>>.>>>>>>>>>>.>>>>>.>>>>>>.......<<<<<<<<<<<......
.....>>>>>.>>>>>>.........................<<<...>>
>.........................<<<<<..<<<<<<<..<<<..>>>
..>>>>.>>.>>>>>>.....<<<<<<...<<<<<<<<<<<<<<<<....
....>>>>>>>.>.>>>>>>>>....>>>>>>..................
...............<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>
>.>>>...>>>>.>>>><<<<<.<<<..>>>.>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wlc The complete structure of the small-subunit processome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
E320 H321 N322 H323 T328 E833 K834 V835 K837 K838 R872 Q876 K880 M884 K886
Binding residue
(residue number reindexed from 1)
E45 H46 N47 H48 T53 E133 K134 V135 K137 K138 R172 Q176 K180 M184 K186
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum5wlc
PubMed28945246
UniProtQ04500|UTP14_YEAST U3 small nucleolar RNA-associated protein 14 (Gene Name=UTP14)

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