Structure of PDB 8oo0 Chain SR Binding Site BS01

Receptor Information
>8oo0 Chain SR (length=128) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVRTKTVKKSAKVIIEKYYPRLTLDFETNKRVCDEIAVISSKRLRNKIAG
YTTHLMKRIQRGPVRGISFKLQEEERERKDQYVPEVSALDFHQNSETGML
DIDQETKDLLKHLGFDSIPVNVIPVTQS
Ligand information
>8oo0 Chain 2 (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauucugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuauacagcgaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuacauggauaaccgugguaauuc
uagagcuaauacaugcugaaaaucccgacuucggaagggauguauuuauu
agauuaaaaaccaaugcccuucggggcuuucuggugauucauaauaacuu
cucgaaucgcacggccuugcgccggcgaugguucauucaaauuucugccc
uaucaacuuucgacggcuggguauuggccagccguggugacaacggguaa
cggaggguuagggcucgaccccggagaaggagccugagaaacggcuacua
cauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacgggga
gguagugacaauaaauacugauacagggcucuuucgggucuuguaauugg
aaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucu
ggugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguug
uugagguuaaaaagcucguaguugaaccuugggccuagcccgccgguacu
ggcugggcugggccuuuccuucuggagaaccgcaugccggugugucgggg
aaccaggacuuuuacucugaacaaauuagaucgcuuaaagaaggccuaug
cuugaauacauuagcauggaauaauagaauaggacgugugguucuauuuu
guugguuucuaggaccgccguaaugauuaauagggacagucgggggcguc
aguauucaauugucagaggugaaauucuuggauuuauugaagacuaacaa
cugcgaaagcauucgccaaggauguuuucauuaaucaggaacgaaaguua
ggggaucgaagacgaucagauaccgucguagucuuaaccauaaacuaugc
cgauuagggaucggacggcguuuauuuuugacccguucggcaccuuacga
uaaaucaaaauguuugggcuccugggggaguauggucgcaaggcugaaac
uuaaagaaauugacggaagggcaccaccagggguggagccugcggcuuaa
uuugacucaacacggggaaacucaccagguccagacacgaugaggauuga
cagauugagagcucuuucuugauuucgugggugguggugcauggccguuc
uuaguugguggagugauuugucugcuuaauugcgauaacgaacgagaccu
uaaccugcuaaauagcccguauugccuuggcaguacgccggcuucuuaga
gggacuaucggcucaagccgauggaaguuugaggcaauaacaggucugug
augcccuuagauguucugggccgcacgcgcgcuacacugacagagccagc
gaguacucccuuggccgagaggcccggguaaucuuguuaaacucugucgu
gcuggggauagagcauugcaauuauugcucuucaacgaggaaucccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacaca
ccgcccgucgcuacuaccgauugaacggcucagugaggcuuucggacugg
cccagagaggucggcaacgaccacucagggccggaaaguuauccaaacuc
ggucguuuagaggaaguaaaagucguaacaaggucuccguaggugaaccu
gcggagggaucauuu
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<..........<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<..<<..<<....<<<........<<.....<..<<.......
>>..>......>>........<<<<<..........>>>>><...<<<<<
<......(((((((.<<<<<..>>>>>.....<......>.>>>>>>...
..>...<<<<.<<<<.....>>>>>>>>....>>>...>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>.
..<<<..>>>.....>>>>>>.........<<<....<<<.....>>>..
>>>.......>.>....<<<<<<<<<<<<<......>>>>>>>>.>>>>>
.....<<..<...........>..>>.........<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>......
...<<<[[.....<.<<...<<<.<<....<<<<<<<<<<<<<<<<..>>
>>>.>>>>>>>>>>>....<<<<<<....<<<...<<..>>....>>>..
..>>>>>>...<<<<<.<<.......<<..<<.......>>.<<<....>
>>....>>......>>.>>..>>>.........<<<.<<<<<<<<<....
.))))))).>>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..
<<..<<<<<<.<...<<<......>>>......>.>>>>>.>.>>.....
..<<....>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<
<<<...<...<<<<.........>>>>...>>>>>>>>..........<<
<.<<.<<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>>...<<
..]]>>...>>.....>>>.>>>.<<<......<<<<....>>>>....>
>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<....
..<<........>>..........<<<<<......<<<<<........<<
.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<<.
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
<<.<<..<<<<..<<<<<<<<<<<<....>>>>>>>>..>>>>..>>>>.
>>....<<<<<<....>>>>>>.......>>>>>....>>>.>>>.....
>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<.....
.<<.....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>..
....<....<<<<<<..........>>>>>>....>.....>>>>>>...
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<.<..<...<<<<
<<<.<<<.<<<<<....>>>>>.>>>.>>>>>>>...>..>.>>..>>>.
>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>
>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oo0 Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R3 V4 R5 T6 K7 F28 K44 R45 L46 N48 K49 R60 R67 S130
Binding residue
(residue number reindexed from 1)		R1 V2 R3 T4 K5 F26 K42 R43 L44 N46 K47 R58 R65 S128
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8oo0, PDBe:8oo0, PDBj:8oo0
PDBsum8oo0
PubMed38267453
UniProtG0S871

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