Structure of PDB 8oo0 Chain SO Binding Site BS01

Receptor Information
>8oo0 Chain SO (length=135) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGPQVREGELVFGVARIFASFNDTFVHVTDLSGRETICRVTGGMKVKADR
DESSPYAAMLAAQDVAARCKELGITALHIKIRATGGNGTKTPGPGAQSAL
RALARSGMKIGRIEDVTPTPSDSTRRKGGRRGRRL
Ligand information
>8oo0 Chain 2 (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauucugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuauacagcgaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuacauggauaaccgugguaauuc
uagagcuaauacaugcugaaaaucccgacuucggaagggauguauuuauu
agauuaaaaaccaaugcccuucggggcuuucuggugauucauaauaacuu
cucgaaucgcacggccuugcgccggcgaugguucauucaaauuucugccc
uaucaacuuucgacggcuggguauuggccagccguggugacaacggguaa
cggaggguuagggcucgaccccggagaaggagccugagaaacggcuacua
cauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacgggga
gguagugacaauaaauacugauacagggcucuuucgggucuuguaauugg
aaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucu
ggugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguug
uugagguuaaaaagcucguaguugaaccuugggccuagcccgccgguacu
ggcugggcugggccuuuccuucuggagaaccgcaugccggugugucgggg
aaccaggacuuuuacucugaacaaauuagaucgcuuaaagaaggccuaug
cuugaauacauuagcauggaauaauagaauaggacgugugguucuauuuu
guugguuucuaggaccgccguaaugauuaauagggacagucgggggcguc
aguauucaauugucagaggugaaauucuuggauuuauugaagacuaacaa
cugcgaaagcauucgccaaggauguuuucauuaaucaggaacgaaaguua
ggggaucgaagacgaucagauaccgucguagucuuaaccauaaacuaugc
cgauuagggaucggacggcguuuauuuuugacccguucggcaccuuacga
uaaaucaaaauguuugggcuccugggggaguauggucgcaaggcugaaac
uuaaagaaauugacggaagggcaccaccagggguggagccugcggcuuaa
uuugacucaacacggggaaacucaccagguccagacacgaugaggauuga
cagauugagagcucuuucuugauuucgugggugguggugcauggccguuc
uuaguugguggagugauuugucugcuuaauugcgauaacgaacgagaccu
uaaccugcuaaauagcccguauugccuuggcaguacgccggcuucuuaga
gggacuaucggcucaagccgauggaaguuugaggcaauaacaggucugug
augcccuuagauguucugggccgcacgcgcgcuacacugacagagccagc
gaguacucccuuggccgagaggcccggguaaucuuguuaaacucugucgu
gcuggggauagagcauugcaauuauugcucuucaacgaggaaucccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacaca
ccgcccgucgcuacuaccgauugaacggcucagugaggcuuucggacugg
cccagagaggucggcaacgaccacucagggccggaaaguuauccaaacuc
ggucguuuagaggaaguaaaagucguaacaaggucuccguaggugaaccu
gcggagggaucauuu
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<..........<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<..<<..<<....<<<........<<.....<..<<.......
>>..>......>>........<<<<<..........>>>>><...<<<<<
<......(((((((.<<<<<..>>>>>.....<......>.>>>>>>...
..>...<<<<.<<<<.....>>>>>>>>....>>>...>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>.
..<<<..>>>.....>>>>>>.........<<<....<<<.....>>>..
>>>.......>.>....<<<<<<<<<<<<<......>>>>>>>>.>>>>>
.....<<..<...........>..>>.........<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>......
...<<<[[.....<.<<...<<<.<<....<<<<<<<<<<<<<<<<..>>
>>>.>>>>>>>>>>>....<<<<<<....<<<...<<..>>....>>>..
..>>>>>>...<<<<<.<<.......<<..<<.......>>.<<<....>
>>....>>......>>.>>..>>>.........<<<.<<<<<<<<<....
.))))))).>>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..
<<..<<<<<<.<...<<<......>>>......>.>>>>>.>.>>.....
..<<....>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<
<<<...<...<<<<.........>>>>...>>>>>>>>..........<<
<.<<.<<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>>...<<
..]]>>...>>.....>>>.>>>.<<<......<<<<....>>>>....>
>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<....
..<<........>>..........<<<<<......<<<<<........<<
.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<<.
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
<<.<<..<<<<..<<<<<<<<<<<<....>>>>>>>>..>>>>..>>>>.
>>....<<<<<<....>>>>>>.......>>>>>....>>>.>>>.....
>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<.....
.<<.....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>..
....<....<<<<<<..........>>>>>>....>.....>>>>>>...
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<.<..<...<<<<
<<<.<<<.<<<<<....>>>>>.>>>.>>>>>>>...>..>.>>..>>>.
>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>
>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8oo0 Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		N37 D38 G48 R49 T51 R54 T56 M59 D64 T134 S136 D137 T139 R140 K142 R145 R146 R148 R149 L150
Binding residue
(residue number reindexed from 1)		N22 D23 G33 R34 T36 R39 T41 M44 D49 T119 S121 D122 T124 R125 K127 R130 R131 R133 R134 L135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8oo0, PDBe:8oo0, PDBj:8oo0
PDBsum8oo0
PubMed38267453
UniProtG0SFL1

[Back to BioLiP]