Structure of PDB 7ug7 Chain SO Binding Site BS01

Receptor Information
>7ug7 Chain SO (length=88) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHH
SRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
Ligand information
>7ug7 Chain 16 (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaauugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgaacgguaacagguuugcugacgaguggcggacgggu
gaguaaugucugggaaacugccugauggagggggauaacuacuggaaacg
guagcuaauaccgcauaacgucgcaagaccaaagagggggaccuucgggc
cucuugccaucggaugugcccagaugggauuagcuaguaggugggguaac
ggcucaccuaggcgacgaucccuagcuggucugagaggaugaccagccac
acuggaacugagacacgguccagacuccuacgggaggcagcaguggggaa
uauugcacaaugggcgcaagccugaugcagccaugccgcguguaugaaga
aggccuucggguuguaaaguacuuucagcggggaggaagggaguaaaguu
aauaccuuugcucauugacguuacccgcagaagaagcaccggcuaacucc
gugccagcagccgcgguaauacggagggugcaagcguuaaucggaauuac
ugggcguaaagcgcacgcaggcgguuuguuaagucagaugugaaaucccc
gggcucaaccugggaacugcaucugauacuggcaagcuugagucucguag
agggggguagaauuccagguguagcggugaaaugcguagagaucuggagg
aauaccgguggcgaaggcggcccccuggacgaagacugacgcucaggugc
gaaagcguggggagcaaacaggauuagauacccugguaguccacgccgua
aacgaugucgacuuggagguugugccggcguggcuuccggagcuaacgcg
uuaagucgaccgccuggggaguacggccgcaagguuaaaacucaaaugaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaugcaa
cgcgaagaaccuuaccuggucuugacauccacggaaguuuucagagauga
gaaugugccuucgggaaccgugagacaggugcugcauggcugucgucagc
ucguguugugaaauguuggguuaagucccgcaacgagcgcaacccuuauc
cuuuguugccagcgguccggccgggaacucaaaggagacugccagugaua
aacuggaggaagguggggaugacgucaagucaucauggcccuuacgacca
gggcuacacacgugcuacaauggcgcauacaaagagaagcgaccucgcga
gagcaagcggaccucauaaagugcgucguaguccggauuggagucugcaa
cucgacuccaugaagucggaaucgcuaguaaucguggaucagaaugccac
ggugaauacguucccgggccuuguacacaccgcccgucacaccaugggag
uggguugcaaaagaaguagguagcuuaaccuucgggagggcgcuuaccac
uuugugauucaugacuggggugaagucguaacaagguaaccguaggggaa
ccugcgguuggauc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<..<<<.....>>>>>..>>>>>......<<
.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<......>
>>>>......>>.>.....<<<....>>>....<<<<<<..<<....>>>
>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<......
...>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>
.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>.....
....<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<<.....
.<<<<....>>>>.....>>>>...<.<<<<<......<.<<<<<<<<..
.....>>>>>>>>.>........>>>>>....>..<<<<<(((...<<<<
<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>........
..<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<
<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<..
.<<<<<<<....<<<<<<<<...<<<......>>>......>>>>>>>>.
..........<<....>>.>>>>>>>..>>>>.>>>>...>>>...>>>>
....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>....
......<<<<<<.<<<<<<<<<<<<..>>>>>>>>>>>>..<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<.<<<<<..<<<<<<<....>>>
>>>>...<<....>>..>>>>>.>...<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<...<<..<<<.....>>>>>....>>>>>>>.....<<<<<....
.>>>>>........>>>>.........>>>...>>>>>>>>....>>>>>
>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<...<<<....
>>>...>>....>>>.....>>>>>>>......<....<<<<<<<.....
...>>>>>>>....>.....>>>>>>....<<<<<<<.........>>>>
>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<
<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>>>>>>>>>>...
>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....
>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ug7 The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Resolution2.58 Å
Binding residue
(original residue number in PDB)		S2 N20 D21 T22 G23 Q28 L31 Q35 H38 H42 H46 K48 D49 H50 H51 S52 R54 G55 K65 Y69
Binding residue
(residue number reindexed from 1)		S1 N19 D20 T21 G22 Q27 L30 Q34 H37 H41 H45 K47 D48 H49 H50 S51 R53 G54 K64 Y68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ug7, PDBe:7ug7, PDBj:7ug7
PDBsum7ug7
PubMed35500116
UniProtP0ADZ4|RS15_ECOLI Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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