Structure of PDB 6lqv Chain SM Binding Site BS01

Receptor Information
>6lqv Chain SM (length=123) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSERAFQKQPHIRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKI
LTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVG
DIVTVGQCRPISKTVRFNVVKVS
Ligand information
>6lqv Chain SA (length=950) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcagcuggggggagu
auggucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccagg
aguggagccugcggcucaacacggggaaacucaccagguccagacacaau
aaggauugacauucuugauuuugugggugguggugcauugaugcccuugu
ucugggccacgcgcgcuacacugacggagccagcgagucuagugaaacuc
cgucgugcuggcaacgaggaauuccuaguaagcgcaagucaucagcuugc
guugauuacgucccugcccuuuguacacaccgcccgucgcuaguaccgau
ugaauggcuuagugaggcgacaaacuuggucauuuagaggaacuaaaagu
............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<....>........
............<<.........>>.....<<<<<<<<<<<<..<<.<<<
<<<..<<<.<<<<.......................<<.<....<<<<<.
.......<.....>......>>>>>......<<<........>>>...>.
>>.......>>>>.>>>.....<<<<<<<..................>>>
>>>>................>>>>>>....<<<<<<<<.......>>>>>
>>>......>>...>>>>>>>............>>>>>..<<<<.<<...
..<<<<<<<.<<<..<....>..>>>.>>>>>>>....>>.>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqv Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution4.8 Å
Binding residue
(original residue number in PDB)		F13 K56 K57 S65 R67 K79 M80 R82 T83 E101 K102 R103 H104 K105 N106 R129 P130 I131 S132 K133 R136
Binding residue
(residue number reindexed from 1)		F6 K36 K37 S45 R47 K59 M60 R62 T63 E81 K82 R83 H84 K85 N86 R109 P110 I111 S112 K113 R116
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqv, PDBe:6lqv, PDBj:6lqv
PDBsum6lqv
PubMed32943522
UniProtP0CX47|RS11A_YEAST Small ribosomal subunit protein uS17A (Gene Name=RPS11A)

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