Structure of PDB 8rxh Chain SL Binding Site BS01 |
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| >8rxh Chain S1 (length=1844)
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gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaaa
ucagacguaaucugccgcaaaaaucuugcggccgcaaaauuggauaacuu
ggcgaaacgccaagcuaauacaugaaccaaccggguguucuccacgugag
acgcccagcgaaugaaugacaguaaaaccaaugccuugcaguaacaccca
gcaguguugacucaauucauuccgugcgaaagccggcuuguuccggcguc
uuuugacgaacaacugcccuaucagcuggugauggccguguaguggacug
ccauggcguugacgggagcgggggauuaggguucgauuccggagagggag
ccugagaaauagcuaccacuucuacggagggcagcaggcgcgcaaauugc
ccaaugucaaaacaaaacgaugaggcagcgaaaagaaauagaguuguuug
ucauuucaaugggggauauuuaaacccauccaauaucgaguaacaauugg
aggacaagucuggugccagcacccgcgguaauuccagcuccaaaagcgua
uauuaaugcuguugcuguuaaaggguucguaguugaacugugggcugugc
agggcccuugcagcccgugaaaaagaaacaagaaacacgggagugggucg
caugucaugcaugccagggggcguccgugauuuuuacugugacuaaagaa
gcgugacuaaagcagucauuugacuugaauuagaaagcaugggauaacaa
aggagcagccucuaggcuaccguuucggcuuuuguuguuuuuaaaggucu
auuggagauuauggagcuguuucccacggugugacggccucuaggaauga
aggaggguaguucgggggagaacguacuggggcgucagaggugaaauucu
uagaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuu
ccucaaucaagaaccaaaguguggagaucgaagaugauuagaaaccauug
uaguccacacugcaaacgaugacacccaugaauuggggauacuuaguauc
uuuacgggaauauccucagcacgcacgcgaaagcuuugagguuacagucu
caggggggaguacguucgcaagagugaaacuuaaagaaauugacggaaug
gcaccacaagacguggagcgugcgguuuaauuugacucaacacggggaac
uuuaccagauccggacaggaugagauugacagauugaguguucuuucucg
auucccugaaugguggugcauggccgcuuauggucgguggagugauuugu
uugguugauuccgucaacggacgagauccaagcugcccaguagaauucag
aauugcccauaggauagcgcauucggucgaauucuucucugcgggauucc
uuuguaauugcacaaggugaaauuuugggcaacagcaggucugugaugcu
ccucaauguucugggcgacacgcgcacuacaaugucagugagaacaagaa
aaacgaucgaaccuacuugaucaaaagaguggggaaaccccggaaucaca
uagacccacuugggaccgaggauugcaauuauuggucgcgcaacgaggaa
ugucucguaggcgcagcucaucaaacugugccgauuacgucccugccauu
uguacacaccgcccgucguuguuuccgaugauggugcaauacaggugauc
ggacaggcgcccgaaaguucaccgauauuucuucaauagaggaagcaaaa
gucguaacaagguagcuguaggggaaccugcagcugggacauuu |
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<..<....
.<<<..<<..<<...<<.<<.....<<<<<..>>>>>...<<.....<<<
<<<.....>>>>>>......>>..........<<<<<.<<<<.....>>>
>>>>>>.<<<<<<<<<<.....(((((.((((<<...>>...........
..............>>>>>>>>...>>....<<<<<......>>>>>...
>>.>>..>>>>..>>>.<<<....<<<....<<<<<.<<.......>>.>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>>>>.<<.<<
<..........>>>.>>.<<<<....>>>>...>>>>>>.........<<
<....<<<..........>>>..>>>..>....>>>....<<<.<<....
.>>.>>>.....<<<<............>>>.....>.........<<<<
<<<........((.....((..>>)).......))...>>>>>..>>>>>
>>>>>.........<<<[[.....<<<<...<<<.......<...<<.<.
.<..>.>.>>...>...................<...............<
<<<.......>>>>.............>.....<<<<<<<<.......<<
...<.......>..<<<....>>>.....>>......>>>>>..>>>...
........<<..<<<<<<.<<<...>>>.....)))).)))))..>>>>>
>..>>.......<<<<<<<.<.<<...>>.>...>>>.>>>>........
....<<<<<..<<...<<<<<<<<..<<<<.<<<...<<<......>>>.
.....>>>.>>>.>.>>.......<<....>>.>>>>>>...>>>>>.>>
....>>>...>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>.
..>>>>>>>>>.........<<<.<<..<<..<<<<<<<........<<.
.........>>.>>>>>>>..>>...<<..]]>>.....>>.....>>>.
>>>.<<<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<
<<<..<<.<<<<<<..<<.<<<<<<<......<<........>>......
....<<<<<.<....<<<<........<<.<<<........>>>.>>...
....>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>..
.<<<......>>>...>>.>>>....<<<<<.<<<<.....<<<<<<<.<
<<<.................>>>>....>>>>>>>.....>>>>....<<
<<.<<......>>>>>>.......>>>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>...>>.>>>>>.>>.....<<<.<<<.......<..
...<<..>>..<<<<<<<........>>>>>>>....>........>>>.
..>>>......<....<<<..<..........>..>>>.....>.....>
>>>>>....<<<<<<<.........>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.<
...<.<....>.>...>.>>>>>..>>>>.>.>>>.>>..>>>>>>>>..
>.>>...>.....<<<<<<<<<....>>>>>>>>>......... |
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| PDB | 8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. |
| Resolution | 2.93 Å |
Binding residue
(original residue number in PDB) | Y7 Q11 Q13 K17 K18 K19 T20 I22 A30 A31 Q32 C33 N34 I35 K36 N38 L42 Q43 L46 P47 R51 M55 S67 G77 G78 G79 Q80 V81 S82 Q83 P127 R128 R129 C130 E131 P132 K133 K134 W135 G136 R137 S139 R141 T142 R143 F144 T145 K146 S147 Y148 R149 |
Binding residue
(residue number reindexed from 1) | Y2 Q6 Q8 K12 K13 K14 T15 I17 A25 A26 Q27 C28 N29 I30 K31 N33 L37 Q38 L41 P42 R46 M50 S62 G72 G73 G74 Q75 V76 S77 Q78 P122 R123 R124 C125 E126 P127 K128 K129 W130 G131 R132 S134 R136 T137 R138 F139 T140 K141 S142 Y143 R144 |
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