Structure of PDB 7wtl Chain SL Binding Site BS01

Receptor Information
>7wtl Chain SL (length=146) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEG
SYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYE
KRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAG
Ligand information
>7wtl Chain C2 (length=1102) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaaauacagugaaacugcgaauggcucauua
aaucaguuaucguuuauuugauaguuccucuacaugguauaacuguggua
auucuagagcuaauacaugcuuaaaaucucgacccuuuggaagagaugua
uuuauuagauaaaaaaucaaugucuucggacucuuugaugauucauaaua
acuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuucu
gcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacgg
guaacggggaauaaggguucgauuccggagagggagccugagaaacggcu
accacauccaaggaaggcagcaggcgcgcaaauuacccaauccuaauuca
gggagguagugacaauaaauaacgauacagggucuuguaauuggaaugag
uacaauguaaauaccuuaacgaggaacaauuggagggcaagucuggugcc
agcagccgcgguaauuccagcuccaauagcguauauuauguugcaguuaa
aaagcucguaguugaacuuugggcccgguuaacggggccuuuccuucugg
cuaaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcaggcgu
auugcucgaauauauuagcauggaauaauagaauaggacguuugguucua
uuuuguugguuucuaggaccaucguaaugauuaauagggacggucggggg
caucaguauucaauugucagaggugaaauucuuggauuuauugaagacua
acuacugcgaaagcauuugccaaggacguuuucauuaaucaagaacgaaa
guuaggggaucgaagaugaucagauaccgucguagucuuaaccauaaacu
augccgacuagggaucgggugguguuuuuuuaaugacccacucggcaccu
uacgagaaaucaaagucuuuggguucuggggggaguauggucgcaaggcu
gaaacuuaaaggaauugagguuuccguaggugaaccugcggaaggaucau
ua
...<<<<<.{{[[[[>>>>>[[[..((((((................[[[
.[[[..<<....<<....<<.......>>...>>.>>......{{.....
...[[[..{{..{{....[[[...............<<....<<.<<<..
...>>>.>>.....>>.........<<<<<..<<....>>..>>>>>[..
.((((((......<<<<<<<<<<<....>>>....<<......>>)))))
).....]...<<<<..<<<.....>>>.>>>>....]]]...}}}}..]]
].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>
>...<<<.<<<<....>>>>....>>>.}}.<<.<<<..........>>>
.>>.<.<<<..>>>.>...]]]]]].........<<<....<<<.....>
>>..>>>...............<<<<<<<<....>>>>>.>>>......<
<..<...........>..>>.........<<<<<........<<<<.<<<
.<<....>>>>>....>>>>.>>>>>..)))))).]]].....[[[{{..
.....{{...[[[.{{....<<<<<<.<<..>>.>>>>>>....<<<<<<
.....>>>>>>...<<<<<.<<.......<<...<.......>..<<<..
...>>>....>>......>>.>>..>>>.........[[[..((((((((
....>>>>>>>>.)))))))).]]].....}}....<<<<<<.<<...<<
<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..>>.
......<<....>>...>>>>...>>>>>.>>>...]]]...}}......
<<<<<<..<.<...<<<...........>>>...>>>>>>>>........
..<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>
...<<..}}>>...>>.....>>>.]]].<<<......<<<<....>>>>
....>>>..]]]].}}.....<<<<<<<<<....>>>>>>>>>.......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wtl In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
E10 Q14 P17 H18 F20 W34 K36 N37 L40 K57 L63 S65 I66 R67 K69 S77 K79 M80 H81 T83 Y90 H92 K96 Y97 K102 R103 H104 N106 Q127 R129 P130 I131 S132 K133 T134 R136 F137
Binding residue
(residue number reindexed from 1)
E9 Q13 P16 H17 F19 W33 K35 N36 L39 K56 L62 S64 I65 R66 K68 S76 K78 M79 H80 T82 Y89 H91 K95 Y96 K101 R102 H103 N105 Q126 R128 P129 I130 S131 K132 T133 R135 F136
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7wtl, PDBe:7wtl, PDBj:7wtl
PDBsum7wtl
PubMed36263816
UniProtP0CX47|RS11A_YEAST Small ribosomal subunit protein uS17A (Gene Name=RPS11A)

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