Structure of PDB 7d4i Chain SK Binding Site BS01

Receptor Information
>7d4i Chain SK (length=174) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARD
LLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERR
LQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDF
APTSPFGGARPGRVARRNAARKAE
Ligand information
>7d4i Chain SA (length=1337) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucaaag
auuaagccaugcaugucuaaguauaagcaauuuauacagugaaacugcga
aaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagagucuucggacucuuugaugauucauaauaacuuuuc
gaaucgcauggccuugugcuggcgaugguucauucaaauuucugcccuau
caacuuucgaugguaggauaguggccuaccaugguuucaacgggagcagg
cgcgcaaauuacccaauccuaauucagggagguagugacaauaaauaacg
auacagggcccauucgggucuuguaauuggaaugaguacaauguaaauac
cuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgguaa
uuccagcuccaauagcguauauuaagcucguaguugaacugggcccgguu
ggccgguccgauuuucgugacuggccaacggggccuuuccuucugguuua
cuuugaaaaaauuagaguguucaaagcaggcguauugcucgaauauauua
gcauggaauaauagaauaggguuugguucuaucuaggaccaugauuaaua
gggacggucgggggcaucaguauucaauugucagaggugaaauucuugga
uuuauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauu
aaucaagaacguagggaucgggugguguuuuuuuaaugacccacucggca
ccuuggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggc
accaccaggaguggagccugcggcucaacacggggaaacucaccaggucc
agacacaauaaggauugacauucuugauuuugugggugguggugcauuga
ugcccuuguucugggcccgcgcgcuacacugacggagccagcgagucuaa
ccuuggccgagaggucuuggaaacuccgucgugcuggggauagagcauug
uaauuauugcucuucaacgaggaauuccuaguaagcgcaagucaucagcu
ugcguugauuacgucccugcccuuuguacacaccgcccgucgcuaguacc
gauugaauggcuuagugaggccucaggaucugcuuagagaagggggcaac
uccaucucagagcggagaauuuggacaaacuuggucauuuagaggaacua
aauuccguaggugaaccugcggaaggaucauuaaaga
.................................<<<<<<...<.<.....
.....<<<.<<<..<<....<<.....................>>.>>..
.....<<<..<<..<<....<<<..................<.....<<.
<<<.....>>>.>>......>.........<<<<<..<<....>>..>>>
>><...<<<<<<..<<<<..>>>>..............>>>>>>.....>
...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.<<<..
..<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.>>>>>
>.........<<<....<<<.....>>>..>>>.......>.>.....<<
.<<<<..<<<<....>>>>..>>>>..>>......<<..<..........
.>..>>.........<<<<<<.......<<<....>>>............
......>>>>>>..>>>>>>.....<.<<...<<<.<<...<<<<<.<<<
<<<<<<<<<<<...>>>.>>>>>>>>>>>.>>>>>............<<<
<<.<<...........<<.......>>.<<<.....>>>...........
.>>.>>..>>>............<..<.......>..>......>>....
<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>.....
.>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.>>>...
>>>...>>.>..<<<..<<<<<<<<.<<..........>>>>>>>>>>..
>>>..................<<.........>>.....<<<<<<<<<<<
<..<<.<<<<<<..<<<.<<<<.......................<<...
...<<<<<.....................>>>>>......<<<.......
.>>>.....>>......>>>>.>>>.....<<<<<<<.............
<<..<<<<....>>>>..>>...>>>>>>>......<....<<<<<<...
.......>>>>>>....>.....>>>>>>....<<<<<<<.........>
>>>>>>......>>...>>>>>>>............>>>>>..<<<<.<<
....<<<<<<<<.<<<....<<..........<<<.<<<..<<<......
>>>..>>>.>>>..........>>....>>>.>>>>>>>>...>>.>>>>
..<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d4i Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1
Resolution4.0 Å
Binding residue
(original residue number in PDB)		S9 T11 Y12 R17 K37 N38 K39 R44 F71 E72 A75 R82 K120 H124 R126 V127 T130 Q131 H133 Q139 N142 I143 S145 F146 R149 P163 G170 R171 V172 A173 R175 N176
Binding residue
(residue number reindexed from 1)		S1 T3 Y4 R9 K29 N30 K31 R36 F63 E64 A67 R74 K112 H116 R118 V119 T122 Q123 H125 Q131 N134 I135 S137 F138 R141 P155 G162 R163 V164 A165 R167 N168
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0043226 organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7d4i, PDBe:7d4i, PDBj:7d4i
PDBsum7d4i
PubMed
UniProtO13516|RS9A_YEAST Small ribosomal subunit protein uS4A (Gene Name=RPS9A)

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