Structure of PDB 7mqa Chain SG Binding Site BS01

Receptor Information
>7mqa Chain SG (length=389) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETAQEKKLRLAKLYLEQLRQQEEEKAEFEEDQVAGRLKEDVLEQRGRLQK
LVAKEIQAPASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSV
ESGRKLHVIPRAKKKPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQ
SCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETL
FGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDC
IHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEPGLEQPFWI
SSVAALLNTDLVATGSHSSCVRLWQCGEGFRQLDLLCDIPLVGFINSLKF
SSSGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRVP
Ligand information
>7mqa Chain L2 (length=177) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuauacuuucagggaucauaguguguuacuaaaccacgaggaagagag
guagcguuuucuccugagcgugaagccggcuuucuggcguugcuuggcug
caacugccgucagccauugaugaucguucuucucuccguauuggggagug
agagggagagaacgcggucugaguggu
..................................<<<<<.....<<....
...<<<<<<<<<<<<....<.......<<<<....<<<<<<<<......>
>>>>.>>>...>>>>.........>..<<<<<<<<<<.....>>>>>>.>
>>>>>>>>>>>>>>>...>>..>>>>>
Receptor-Ligand Complex Structure
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PDB7mqa Nucleolar maturation of the human small subunit processome.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R143 Q146 R179 R186 R448 K453
Binding residue
(residue number reindexed from 1)		R68 Q71 R104 R111 R369 K374
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0006364 rRNA processing
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtO43818|U3IP2_HUMAN U3 small nucleolar RNA-interacting protein 2 (Gene Name=RRP9)

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