Structure of PDB 7d5s Chain SG Binding Site BS01

Receptor Information
>7d5s Chain SG (length=213) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFEVVEEFTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYV
QVRQPIFVAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVR
IIKHTLDIINVLTDQNPIQVVVDAITNTGPREDTTRVGGGGAARRQAVDV
SPLRRVNQAIALLTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIK
KKDELERVAKSNR
Ligand information
>7d5s Chain SA (length=859) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucacaa
auuagugacaauaaauaacgauacagggcccauucgggucuuguaauugg
aaugaguacaauguaaauaccuuaacgaggaacaauuggagggcaagucu
ggugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguug
uugcaggcucguaguugaacuuagggacggucgggggcaucaguauucaa
uugucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaag
cauuugccaaggacguuuucauuaaucaagaacgaaaguuaggggaucga
agaugaucagauaccgucguagucuuaacuggggggaguauggucgcaag
gcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccug
cggcucaacacggggaaacucaccagguccagacacaauaaggauugaca
uucuugauuuugugggugguggugcauugaugcccuuguucugggccacg
cgcgcuacacugacggagccagcgagucuaaccuuggccgagaggucuug
guaaucuugugaaacuccgucgugcuggggauauucaacgaggaauuccu
aguaagcgcaagucaucagcuugcguugauuacgucccugcccuuuguac
acaccgcccgucgcuaguaccgauugaauggcuuagugaggccucaggau
cugcuuagagaagggggcaacuccaucucagagcggagaauuuggacaaa
cuuggucauuuagaggaacuaaaagucguaacaagguuuccguaggugaa
ccugcggaa
............................<<<<.<<<<<<...........
..................<<<<<<<.<<<<<....>>>>>.>>>.>>>>.
.....<<..<...........>..>>.........<<<<<<.......<<
<....>>>..................>>>>>>..>>>>>>>>>>......
...<..<.<<...<<<.......<<<<<<.<<...<<<<..<<..<<<<<
<.<...<<<......>>>......>.>>>>>>..>>.......<<....>
>...>>>>..>.>>>>.>>>...>>>...>>.>......<<<<<...<..
.<<<<.........>>>>...>>>>>>...>...................
.<<.........>>.....<<<<<<<<<<<<..<<.<<<<<<..<<<.<<
<<.......................<<.<....<<<<<........<...
..>......>>>>>......<<<........>>>...>.>>.......>>
>>.>>>.....<<<<<<<............<<<..<<<<....>>>>..>
>>............>>>>>>>.......................>>>>>>
....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>.....
.......>>>>>..<<<..<<....<.<<<..<.<<<..<.<<......<
<<<<<<.<<<<.<<<<....>>>>.>>>>.>>>>>>>......>>.>..>
>>.>..>>>>....>>..>>>................<<<<<<<<<....
>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d5s Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2)
Resolution4.6 Å
Binding residue
(original residue number in PDB)		H72 A78 K80 R81 K84 R92 N95 M99 R102 N104 G105 K106 K107 R112 N169 R180 I187
Binding residue
(residue number reindexed from 1)		H60 A66 K68 R69 K72 R80 N83 M87 R90 N92 G93 K94 K95 R100 N157 R168 I175
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000054 ribosomal subunit export from nucleus
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006450 regulation of translational fidelity
GO:0030490 maturation of SSU-rRNA
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7d5s, PDBe:7d5s, PDBj:7d5s
PDBsum7d5s
PubMed
UniProtP26783|RS5_YEAST Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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