Structure of PDB 7d5t Chain SF Binding Site BS01

Receptor Information
>7d5t Chain SF (length=247) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNG
REVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGR
FAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVND
TVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLV
HIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRR
Ligand information
>7d5t Chain SA (length=1189) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucaaag
auuaagccaugcaugucuaaguauaagcaauuuauacagugaaacugcga
aaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagagucuucggacucuuugaugauucauaauaacuuuuc
gaaucgcauggccuugugcuggcgaugguucauucaaauuucugcccuau
caacuuucgaugguaggauaguggccuaccaugguuucaacgggagcagg
cgcgcaaauuacccaauccuaauucagggagguagugacaauaaauaacg
auacagggcccauucgggucuuguaauuggaaugaguacaauguaaauac
cuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgguaa
uuccagcuccaauagcguauauuaagcucguaguugaacugggcccgguu
ggccgguccgauuuucgugacuggccaacggggccuuuccuucugguuua
cuuugaaaaaauuagaguguucaaagcaggcguauugcucgaauauauua
gcauggaauaauagaauaggguuugguucuaucuaggaccaugauuaaua
gggacggucgggggcaucaguauucaauugucagaggugaaauucuugga
uuuauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauu
aaucaagaacguagggaucgggugguguuuuuuuaaugacccacucggca
ccuuggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggc
accaccaggaguggagccugcggcgcgcgcuacacugacggagccagcga
aacuccgucgugcugggaacgaggaauuccuaguaagcgcaagucaucag
cuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuagua
ccgauugaauggcuuagugaggccucaggaucugcuuagagaagggggca
acuccaucucagagcggagaauuuggacaaacuuggucauuuagaggaac
uaaauuccguaggugaaccugcggaaggaucauuaaaga
.................................<<<<<<...<.<.....
.....<<<.<<<..<<....<<.....................>>.>>..
.....<<<..<<..<<....<<<..................<.....<<.
<<<.....>>>.>>......>.........<<<<<..<<....>>..>>>
>><...<<<<<<..<<<<..>>>>..............>>>>>>.....>
...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.<<<..
..<<<....<<<<<<<<.......>>>>>>>>>>>......>>>.>>>>>
>.........<<<....<<<.....>>>..>>>.......>.>.....<<
.<<<<..<<<<....>>>>..>>>>..>>......<<..<..........
.>..>>.........<<<<<<.......<<<....>>>............
......>>>>>>..>>>>>>.....<.<<...<<<.<<...<<<<<.<<<
<<<<<<<<<<<...>>>.>>>>>>>>>>>.>>>>>............<<<
<<.<<...........<<.......>>.<<<.....>>>...........
.>>.>>..>>>............<..<.......>..>......>>....
<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>.....
.>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.>>>...
>>>...>>.>..<<<..<<<<<<<<.<<..........>>>>>>>>>>..
>>>..................<<.........>>.....<<<<<<<<<<<
<..<<.<<<<<<..<<<.<<<<.>>>>.>>>.....<<<<<<<.......
..>>>>>>>......<...>.....>>>>>>....<<<<<<<........
.>>>>>>>......>>...>>>>>>>............>>>>>..<<<<.
<<....<<<<<<<<.<<<....<<..........<<<.<<<..<<<....
..>>>..>>>.>>>..........>>....>>>.>>>>>>>>...>>.>>
>>..<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d5t Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
Resolution6.0 Å
Binding residue
(original residue number in PDB)		A13 H16 S24 Y27 P29 R30 A33 G34 K37 R49 N57 G58 M66 K75 R77 K128 L131 K133 K134 T146 R148 K155 R187 D202 V219 T220 R221 I248
Binding residue
(residue number reindexed from 1)		A5 H8 S16 Y19 P21 R22 A25 G26 K29 R41 N49 G50 M58 K67 R69 K120 L123 K125 K126 T138 R140 K147 R179 D194 V211 T212 R213 I240
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032991 protein-containing complex
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7d5t, PDBe:7d5t, PDBj:7d5t
PDBsum7d5t
PubMed
UniProtP0CX35|RS4A_YEAST Small ribosomal subunit protein eS4A (Gene Name=RPS4A)

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