Structure of PDB 6lqu Chain SF Binding Site BS01

Receptor Information
>6lqu Chain SF (length=229) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVK
AILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVH
RITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKI
DLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKD
SLDNTFVTRLNNVFVIGEQGKPYISLPKG
Ligand information
>6lqu Chain SA (length=1242) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcaggcucguaguug
aacuuagggacggucgggggcaucaguauucaauugucagaggugaaauu
cuuggauuuauugaagacuaacuacugcgaaagcauuugccaaggacguu
uucauuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccgu
cguagucuuaacuggggggaguauggucgcaaggcugaaacuuaaaggaa
uugacggaagggcaccaccaggaguggagccugcggcucaacacggggaa
acucaccagguccagacacaauaaggauugacauucuugauuuugugggu
gguggugcauugaugcccuuguucugggccacgcgcgcuacacugacgga
gccagcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuc
cgucgugcuggggauauucaacgaggaauuccuaguaagcgcaagucauc
agcuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuag
uaccgauugaauggcuuagugaggccucaggaucugcuuagagaaggggg
caacuccaucucagagcggagaauuuggacaaacuuggucauuuagagga
acuaaaagucguaacaagguuuccguaggugaaccugcggaa
............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<..<.<<...<<<.
......<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>
>......>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.
>>>...>>>...>>.>......<<<<<...<...<<<<.........>>>
>...>>>>>>...>....................<<.........>>...
..<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<<...............
........<<.<....<<<<<........<.....>......>>>>>...
...<<<........>>>...>.>>.......>>>>.>>>.....<<<<<<
<............<<<..<<<<....>>>>..>>>............>>>
>>>>.......................>>>>>>....<<<<<<<<.....
..>>>>>>>>......>>...>>>>>>>............>>>>>..<<<
..<<....<.<<<..<.<<<..<.<<......<<<<<<<.<<<<.<<<<.
...>>>>.>>>>.>>>>>>>......>>.>..>>>.>..>>>>....>>.
.>>>................<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqu Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		K22 Y27 P29 R30 A33 G34 P35 H36 K37 L38 R49 N57 M66 R77 K133 K134 G135 Y138 R145 T146 R148
Binding residue
(residue number reindexed from 1)		K10 Y15 P17 R18 A21 G22 P23 H24 K25 L26 R37 N45 M54 R65 K121 K122 G123 Y126 R133 T134 R136
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:0032991 protein-containing complex
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqu, PDBe:6lqu, PDBj:6lqu
PDBsum6lqu
PubMed32943522
UniProtP0CX35|RS4A_YEAST Small ribosomal subunit protein eS4A (Gene Name=RPS4A)

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