Structure of PDB 8p5d Chain SDD Binding Site BS01

Receptor Information

>8p5d Chain SDD (length=65) Species: 1358809 (Spraguea lophii 42_110)

MNKQMIKYNADLETTFTVERKDFGRTNRRCRACFAYNGVIRKYDLMICRR
CFREYAGDIGFKIYD

Ligand information

>8p5d Chain S60 (length=1354)

accagguugauucugccugacguggaugcuagucucauagauuuagccau
gcauguguaagcgaagcgauuagugaagcggcggaaggcucaguaacggg
cgaguauuuaaucucuagaaccggacaaccucaggaaacagaggggaaaa
cggaguaagagcauguguuagcaugugaugagaacaacagugcaggagag
uaagaagccaucccaucaguuaguaaguaggguaagggccuauuuagacg
uagacggguacgggggauuaggguuugauuccggagagggagccugagag
acggcuaccagguccaaggacagcagcaggcgcgaaaauuaccgaagccu
ccaagagggcgguagugaagagacgugaaaacaaguguguguaaaaacca
caugaguaacuggaggucaaggcuggugccagcauccgcgguaauaccag
cuccaggagugucuaugaugauugcugcgauuaaaagguccguagucgaa
gaacaguacuuguuuguaauguggcuuaucgagagccgaauagaacgaga
agaguucagaguaaggagcgaaggagggcuagauuauugagcagcgagag
gugaaauuugaugaccugcuuaggaguaacagaggcgaaagcgcuaguca
agaacgaauccgaugaucaaggacguaggcuggaggaucgaagacgauua
gagaccguaguaguuccagcaguaaacgaugccuacgcuguugugguuau
gagcacggcagaagagaaaucuaguagggcuuuggggagaguacgcgcgc
aagcgauaaauuuaaaggaaauugacggaagaacaccacaaggaguggag
ugugcggcuuaauuugacucaacgcgggacagcuuaccauacccgauggc
cgugugagcguaguacgcgauaggucagagaguggugcauggccguuaac
gacgaguggggugaccuuuggguuaaguccgcgaaguagugagaucccua
ggauacgaaaguuaucgacagguguuaaaaacacaggaaggaaggggcaa
gaacaggucagugaugcccuuagaugguaugggcugcacgcgcacuacag
uggucacagcagaaacaaauagaaguaaaugugaucgagagggaaugagc
acuguaaugugcacaggaacgaggaauugcuaguaaucguuaucucauua
agaagcgaugaaugugucccuguucuuuguacacaccgcccgucguuauc
gaagauggaaccaggugcgaacaagugaaagcgagugagugcaggguucu
agaucugauacaagucguaacaaggcagcuguaggagaaccuguagcugg
auca

..<<<<<.[.(((.>>>>>.<<<<<<<<<..<<<<<.<.......<<<.<
<<..<<....<<...<<.....>>...>>.>>......<<.......<<<
<.....<<...<<<<<.<..<<<.....<<<<.<....>.>>>>......
>>>....<..<<<<<<....>>>>>>..>....<<....>>.>.>>>>>.
.>>...>>>.><<<....<<<..<<<<<<<<.......>>>>>>>>>>>.
.....>>>..<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>..<<<<..>>>>....>>>>>>.........<<<....<<<
<...>>>>..>>>...>..>>>>>..........<<<<<.........>>
>>>......<<<<<((....<.<<<<.....<<..))>>.......>>>>
>>>>>>..>>>>>>>>>..........<<<((.....<<<<...<<<...
<<<<....<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>.
...>>>>.......<<<.<<......<<<<<<..<.<<<<<<<<...<<<
......>>>......>>>>>>>>..>........<<....>>.>>>>>>.
....>>..>>>...>>>...>>>>..<.<<<<<<<...<....<<<....
.....>>>....>>>>>>>>..>.......<<<.<<.<<<<<<<<.<<..
>>.>>>>>>>>..<<..))>>..>>..>>>.>>>.<<<.......<<<..
..>>>.....>>>....))).]<<<<<.<<<<<<<..<<..<.<<<..<<
<<<<<<<<......<<........>>..........<<<<<<<...<<<<
<......<<<<...>>>>....>>>>>..<<<.<<<..<<.<<<<<<...
.<<.<..<<<....>>>...<<......>>......>.>>....<<<<..
<..<<<....>>.>.>.....<<<<.....>>>>.........>>>>...
.>>>.>>>.....>>>>>>>>....>>>>>>>...>>.>>>>>>>>....
.<<<<<<<.....................>>>>>>>.........<<.<<
<<......>>>>.>>..........>>>.>.....<<<<<..<<......
.>>.>>>>>......>>...>>>>>>>>>>.>>.......<<.<..<<<<
<.<...<<<<<<..<<<<..<<..<<....>>..>>..>>>>..>>>>>>
...>.>>>>>...>.>>.........<<<<<<<<<....>>>>>>>>>..
....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8p5d Spraguea lophii ribosome
• Resolution: 10.8 Å
• Binding residue (original residue number in PDB): K7 R20 K21 F23 R25 T26 N37 R41 K42 R49 R50 R53 Y64 D65
• Binding residue (residue number reindexed from 1): K7 R20 K21 F23 R25 T26 N37 R41 K42 R49 R50 R53 Y64 D65

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8p5d, PDBe:8p5d, PDBj:8p5d
• PDBsum: 8p5d
• PubMed: 37709902
• UniProt: S7XJB1