Structure of PDB 8a3w Chain SD Binding Site BS01

Receptor Information
>8a3w Chain SD (length=163) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRNYNNFNRVWKAPRRPFEKERLDREMKLCGQYGLRCKREIWRVNMTLSK
MRRTARLLLTLPENHPRRLLEGSAIMRRCHEYGFLDEEKDKLDYVLSLTV
PDILERRLQTIVFKAGLAKSVHHARVLIQQRHIAVAKQIVTIPSFIVRVS
SERHIAFADASPF
Ligand information
>8a3w Chain S1 (length=1663) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaau
cagacguaaucugccgcaaaaaucuugcggcaaaauuggauaacuuggcg
aaacgccaagcuaauacaugaaccaaccgggugucuccgagacgcccagc
gaaugaaugacaaaaccaaugccgcaguaacacccagcaguguugacuca
auucauuccgugcgaaagccggcuuccggcgucuuuugacgaacaacugc
ccuaucagcuggugauggccguguaguggacugccauggcguugacggga
gcgggggauuaggguucgauuccggagagggagccugagaaauagcuacc
acuucuacggagggcagcaggcgcgcaaauugcccaaugucaaaacaaaa
cgaugaggcagcgaaaagaaauagaguuauuucaaugggggauauuuaaa
cccaucccgagacaauuggaggacaagucuggugccagcacccgcgguaa
uuccagcuccaaaagcguauauuaaugcuguugcuguuaaaggguucgua
guugaacugugggcugcagcccgugaaagaaaaacacgggaggggugcau
gucaugcaugccguccgugauuuuuuacugugacuaaagaagcgugacua
aagcagucaugacuugaauuagaaagcaugggauaacaaaggagcuuuuu
aaagguuggagauuauggagcugugcgacaaaugggaaugaaggagggua
guucgggggagaacguacuggggcgucagaggugaaauucuuagaccgca
ccaagacgaacuacagcgaaggcauucuucaaggauaccuuccucaauca
agaaccaaaguguggagaucgaagaugauuagaaaccauuguaguccaca
cugcaaacgaugacacccaugaauuggggauaucuucacguuuucuguuu
uacgcgaaagcuuugagguuacagucucaggggggaguacguucgcaaga
gugaaacuuaaagaaauugacggaauggcaccacaagacguggagcgugc
gguuuaauuugacucaacacggggaacuuuaccagauccggacagggauu
gacagauugaguguucuuucucgauucccugaaugguggugcauggccgc
uuauggucgguggagugauuuguuugguugauuccgucaacggacgagau
ccaagcugcccaguagaauucagaauuauucggaauucuucucugcggga
uuccuuuguagcacaaggugaaauuuugggcaacagcaggucugugaugc
uccucaauguucugggcgacacgcgcacuacaaugucagugagaacaaga
acuacuugaucaaaagaguggggaaaccccggaaucacauagacccacuu
gggaccgaggauugcaauuauuggucgcgcaacgaggaaugucucguagg
cgcagcucaucaaacugugccgauuacgucccugccauuuguacacaccg
cccgucguuguuuccgaugauggugcaauacaggugaucggacgaaaguu
caccgauauuucuucaauagaggaagcaagucguaacaagguagcuguag
gaccugcagcugg
...<<<<<.{.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<..<....
<<<..<<..<<...<<.<<.....<<<<.>>>>...<<.....<<<<<<.
....>>>>>>......>>..........<<<<<<<<<.>>>>>>>>>.<<
<<<<<<<<.....((.{..{<<.>>.........................
>>>>>>>>...>>....<<<<<...>>>>>...>>.>>..>>>>..>>>.
<<<....<<<....<<<<<.<<.......>>.>>>>>>>>......>>>.
.<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.>>
.<<<<....>>>>...>>>>>>.........<<<....<<<.........
.>>>..>>>..>....>>>....<<<....>>>.....<<<<........
....>>>>.......<<<<<((....<.<<<<.....<<..))>>.....
..>>>>>>>>>>..>>>>>>>>>>.........<<<[[.....<<<<...
<<<..<....<........>...........<..............<<<<
.......>>>>.........>...<<<<<<<<.......<<...<.....
..>..<<<..>>>.....>>......>>>>>..>>>..........<<.<
<.<<...}..}.))......>>.>>.>>..........>......<<<<<
..<<...<<<<<<<<..<<<<.<<<...<<<......>>>......>>>.
>>>.>.>>.......<<....>>.>>>>>>...>>>>>.>>....>>>..
.>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>
>>.........<<<.<<...<<<<.<<<<<<.<....>.>>>>>>.>>>>
...<<..]]>>.....>>.....>>>.>>>.<<<......<<<<....>>
>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<.<<<<
<<<......<<........>>..........<<<<<.<....<<<<....
<<.<<<........>>>.>>.......>>>>...<<.<<<..<<.<<<<<
<....<<<.<<<<......>>...<<<......>>>...>>.>>>....<
<<<<.<<<<.....<<<<<<<.<<<<.>>>>.>>>>>>>.....>>>>..
..<<<<........>>>>.......>>>>>....>>>.>>>.....>>>>
>>>.....>.>>>>>...>>.>>>>>.>>.....<<<.<<<.......<.
..<.<.<..........>.>.>....>........>>>...>>>......
<....<<<..<..........>..>>>.....>.....>>>>>>....<<
<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>.....
..<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.<........>.>
>>>>..>>>>.>.>>>.>>..>>>>>>>>>.>>.........<<<<<<<<
<.>>>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)		M1 R2 N3 Y4 N5 N6 F7 N8 R9 V10 P17 F18 R36 K38 R39 R43 E71 R77 R78 S120 H123 R125 Q130 R131 H132 I142 S144 F145 R148
Binding residue
(residue number reindexed from 1)		M1 R2 N3 Y4 N5 N6 F7 N8 R9 V10 P17 F18 R36 K38 R39 R43 E71 R77 R78 S120 H123 R125 Q130 R131 H132 I142 S144 F145 R148
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0043226 organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4QIM3

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