Structure of PDB 6lqq Chain SC Binding Site BS01

Receptor Information
>6lqq Chain SC (length=230) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQKKRVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGR
VVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMV
RKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAI
RKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRK
VKLLKQPKFDVGALMALHGEGSGEEKGKKV
Ligand information
>6lqq Chain SA (length=1323) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcagaagcucguagu
ugaacuggcccgguuggccgguccggauuuccaacggggccuugguucua
uuuucuaggacugauuaauagggacggucgggggcaucaguauucaauug
ucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaagcau
uugccaaggacguuuucauuaaucaagaacgaccauaaacuaugccgacu
agggaucgggugguguuuuuuuaaugacccacucggcaccuuacgagaac
uggggggaguauggucgcaaggcugaaacuuaaaggaauugacggaaggg
caccaccaggaguggagccugcggcucaacacggggaaacucaccagguc
cagacacaauaaggauugacauucuugauuuugugggugguggugcauug
augcccuuguucugggccacgcgcgcuacacugacggagccagcgagucu
aaccuuggccgagaggucuugguaaucuugugaaacuccgucgugcuggc
aacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguc
ccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuag
ugaggccucaggaucugcuuagagaagggggcaacuccaucucagagcgg
agaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagg
uuuccguaggugaaccugcggaa
............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<....<.<<...<<
<.<<..<<<<<.<<<<<..<.......>..>>>>>.>>>>>.<..<<..<
...>..>>.>....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<
...<<<......>>>......>.>>>>>>..>>.......<<....>>..
.>>>>...>>>>>.>>>...>>>...>>.>...............<<...
<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>..>>.....
.>....................<<.........>>.....<<<<<<<<<<
<<..<<.<<<<<<..<<<.<<<<.......................<<.<
....<<<<<........<.....>......>>>>>......<<<......
..>>>...>.>>.......>>>>.>>>.....<<<<<<<...........
.<<<..<<<<....>>>>..>>>............>>>>>>>........
........>>>>>>....<<<<<<<<.......>>>>>>>>......>>.
..>>>>>>>............>>>>>..<<<<.<<.....<<<<<<<.<<
<..<.<<......<<<<<<<...<<.<<<......>>>.>>...>>>>>>
>......>>.>..>>>.>>>>>>>....>>.>>>>...............
.<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqq Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		K17 P23 K27 V114 K116 W117 Q118 L120 N124 R136 F138 Q146 N148 Q149 V150 K151 H153 Y155 Q157 S158 S159 R165 K202 D203 I204 F205 P206 K216
Binding residue
(residue number reindexed from 1)		K3 P9 K13 V100 K102 W103 Q104 L106 N110 R122 F124 Q132 N134 Q135 V136 K137 H139 Y141 Q143 S144 S145 R151 K188 D189 I190 F191 P192 K202
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqq, PDBe:6lqq, PDBj:6lqq
PDBsum6lqq
PubMed32943522
UniProtP33442|RS3A1_YEAST Small ribosomal subunit protein eS1A (Gene Name=RPS1A)

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