Structure of PDB 8oo0 Chain SB Binding Site BS01

Receptor Information
>8oo0 Chain SB (length=232) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGKNKRLSKGKKGLKKKVQDPFTRKDWYNIKAPAPFAVRDVGKTLVNRTT
GLKNANDALKGRIFEVCLADLQKDEDHAFRKIKLRVDEVQGKNCLTNFHG
LDFTTDKLRSLVRKWQTLIEANVTVTTTDHYLLRLFAIAFTKRRPNQIKK
TTYAQSSQIRAIRRKMVEIIQREAASCTLHQLVSKLIPEVIGREIEKATQ
GIYPLQNVHIRKVKLLKQPKFDLGALMALHGE
Ligand information
>8oo0 Chain 2 (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauucugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuauacagcgaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuacauggauaaccgugguaauuc
uagagcuaauacaugcugaaaaucccgacuucggaagggauguauuuauu
agauuaaaaaccaaugcccuucggggcuuucuggugauucauaauaacuu
cucgaaucgcacggccuugcgccggcgaugguucauucaaauuucugccc
uaucaacuuucgacggcuggguauuggccagccguggugacaacggguaa
cggaggguuagggcucgaccccggagaaggagccugagaaacggcuacua
cauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacgggga
gguagugacaauaaauacugauacagggcucuuucgggucuuguaauugg
aaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucu
ggugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguug
uugagguuaaaaagcucguaguugaaccuugggccuagcccgccgguacu
ggcugggcugggccuuuccuucuggagaaccgcaugccggugugucgggg
aaccaggacuuuuacucugaacaaauuagaucgcuuaaagaaggccuaug
cuugaauacauuagcauggaauaauagaauaggacgugugguucuauuuu
guugguuucuaggaccgccguaaugauuaauagggacagucgggggcguc
aguauucaauugucagaggugaaauucuuggauuuauugaagacuaacaa
cugcgaaagcauucgccaaggauguuuucauuaaucaggaacgaaaguua
ggggaucgaagacgaucagauaccgucguagucuuaaccauaaacuaugc
cgauuagggaucggacggcguuuauuuuugacccguucggcaccuuacga
uaaaucaaaauguuugggcuccugggggaguauggucgcaaggcugaaac
uuaaagaaauugacggaagggcaccaccagggguggagccugcggcuuaa
uuugacucaacacggggaaacucaccagguccagacacgaugaggauuga
cagauugagagcucuuucuugauuucgugggugguggugcauggccguuc
uuaguugguggagugauuugucugcuuaauugcgauaacgaacgagaccu
uaaccugcuaaauagcccguauugccuuggcaguacgccggcuucuuaga
gggacuaucggcucaagccgauggaaguuugaggcaauaacaggucugug
augcccuuagauguucugggccgcacgcgcgcuacacugacagagccagc
gaguacucccuuggccgagaggcccggguaaucuuguuaaacucugucgu
gcuggggauagagcauugcaauuauugcucuucaacgaggaaucccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacaca
ccgcccgucgcuacuaccgauugaacggcucagugaggcuuucggacugg
cccagagaggucggcaacgaccacucagggccggaaaguuauccaaacuc
ggucguuuagaggaaguaaaagucguaacaaggucuccguaggugaaccu
gcggagggaucauuu
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<..........<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<..<<..<<....<<<........<<.....<..<<.......
>>..>......>>........<<<<<..........>>>>><...<<<<<
<......(((((((.<<<<<..>>>>>.....<......>.>>>>>>...
..>...<<<<.<<<<.....>>>>>>>>....>>>...>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>.
..<<<..>>>.....>>>>>>.........<<<....<<<.....>>>..
>>>.......>.>....<<<<<<<<<<<<<......>>>>>>>>.>>>>>
.....<<..<...........>..>>.........<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>......
...<<<[[.....<.<<...<<<.<<....<<<<<<<<<<<<<<<<..>>
>>>.>>>>>>>>>>>....<<<<<<....<<<...<<..>>....>>>..
..>>>>>>...<<<<<.<<.......<<..<<.......>>.<<<....>
>>....>>......>>.>>..>>>.........<<<.<<<<<<<<<....
.))))))).>>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..
<<..<<<<<<.<...<<<......>>>......>.>>>>>.>.>>.....
..<<....>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<
<<<...<...<<<<.........>>>>...>>>>>>>>..........<<
<.<<.<<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>>...<<
..]]>>...>>.....>>>.>>>.<<<......<<<<....>>>>....>
>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<....
..<<........>>..........<<<<<......<<<<<........<<
.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<<.
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
<<.<<..<<<<..<<<<<<<<<<<<....>>>>>>>>..>>>>..>>>>.
>>....<<<<<<....>>>>>>.......>>>>>....>>>.>>>.....
>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<.....
.<<.....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>..
....<....<<<<<<..........>>>>>>....>.....>>>>>>...
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<.<..<...<<<<
<<<.<<<.<<<<<....>>>>>.>>>.>>>>>>>...>..>.>>..>>>.
>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>
>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oo0 Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K7 L9 K11 K13 K17 K18 R115 K116 W117 Q118 R136 R146 N148 K151 Y155 Q157 S158 S159 K199 G203 Y205 K216
Binding residue
(residue number reindexed from 1)		K5 L7 K9 K11 K15 K16 R113 K114 W115 Q116 R134 R144 N146 K149 Y153 Q155 S156 S157 K197 G201 Y203 K214
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8oo0, PDBe:8oo0, PDBj:8oo0
PDBsum8oo0
PubMed38267453
UniProtG0S7T8

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