Structure of PDB 7olc Chain SB Binding Site BS01

Receptor Information
>7olc Chain SB (length=232) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGKNKRLSKGKKGLKKKVQDPFTRKDWYNIKAPAPFAVRDVGKTLVNRTT
GLKNANDALKGRIFEVCLADLQKDEDHAFRKIKLRVDEVQGKNCLTNFHG
LDFTTDKLRSLVRKWQTLIEANVTVTTTDHYLLRLFAIAFTKRRPNQIKK
TTYAQSSQIRAIRRKMVEIIQREAASCTLHQLVSKLIPEVIGREIEKATQ
GIYPLQNVHIRKVKLLKQPKFDLGALMALHGE
Ligand information
>7olc Chain 2 (length=1765) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauucugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuauacagcgaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuacauggauaaccgugguaauuc
uagagcuaauacaugcugaaaaucccgacuucggaagggauguauuuauu
agauuaaaaaccaaugcccuucggggcuuucuggugauucauaauaacuu
cucgaaucgcacggccuugcgccggcgaugguucauucaaauuucugccc
uaucaacuuucgacggcuggguauuggccagccguggugacaacggguaa
cggaggguuagggcucgaccccggagaaggagccugagaaacggcuacua
cauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacacgggga
gguagugacaauaaauacugauacagggcucuuucgggucuuguaauugg
aaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucu
ggugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguug
uugagguuaaaaagcucguaguugaaccuugggccuagcccgccgguacu
ggcugggcugggccuuuccuucuggagaaccgcaugccggugugucgggg
aaccaggacuuuuacucugaacaaauuagaucgcuuaaagaaggccuaug
cuugaauacauuagcauggaauaauagaauaggacgugugguucuauuuu
guugguuucuaggaccgccguaaugauuaauagggacagucgggggcguc
aguauucaauugucagaggugaaauucuuggauuuauugaagacuaacaa
cugcgaaagcauucgccaaggauguuuucauuaaucaggaacgaaaguua
ggggaucgaagacgaucagauaccgucguagucuuaaccauaaacuaugc
cgauuagggaucggacggcguuuauuuuugacccguucggcaccuuacga
uaaaucaaaauguuugggcuccugggggaguauggucgcaaggcugaaac
uuaaagaaauugacggaagggcaccaccagggguggagccugcggcuuaa
uuugacucaacacggggaaacucaccagguccagacacgaugaggauuga
cagauugagagcucuuucuugauuucgugggugguggugcauggccguuc
uuaguugguggagugauuugucugcuuaauugcgauaacgaacgagaccu
uaaccugcuaaauagcccguauugccuuggcaguacgccggcuucuuaga
gggacuaucggcucaagccgauggaaguuugaggcaauaacaggucugug
augcccuuagauguucugggccgcacgcgcgcuacacugacagagccagc
gaguacucccuuggccgagaggcccggguaaucuuguuaaacucugucgu
gcuggggauagagcauugcaauuauugcucuucaacgaggaaucccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacaca
ccgcccgucgcuacuaccgauugaacggcucagugaggcuuucggacugg
cccagagaggucggcaacgaccacucagggccggaaaguuauccaaacuc
ggucguuuagaggaaguaaaagucguaacaaggucuccguaggugaaccu
gcggagggaucauuu
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<..<<..<<....<<<........<<.....<..<<.......
>>..>......>>........<<<<<..........>>>>><...<<<<<
<......(((((((.<<<<....>>>>..............>>>>>>...
..>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>.
<.<<<..>>>.>...>>>>>>.........<<<....<<<.....>>>..
>>>..>....>.>....<<<<<<<<<<<<<......>>>>>>>>.>>>>>
.....<<..<...........>..>>.........<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>......
...<<<[[.....<.<<...<<<.<<....<<<<<<<<<<<<<<<<..>>
>>>.>>>>>>>>>>>....<<<<<<....<<<...<<..>>....>>>..
..>>>>>>...<<<<<.<<.......<<..<<.......>>.<<<....>
>>....>>......>>.>>..>>>.........<<<.<<<<<<<<<....
.))))))).>>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..
<<..<<<<<<.<...<<<......>>>......>.>>>>>.>.>>.....
..<<....>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<
<<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<<
<.<<.<<<..<<<<<<<<.<<<.......>>>>>>>>>>>..>>>...<<
..]]>>...>>.....>>>.>>>.<<<......<<<<....>>>>....>
>>..]]]].}<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<....
..<<........>>..........<<<<<......<<<<<........<<
.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<<.
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
<<.<<..<<<<..<<<<<<<<<<<<....>>>>>>>>..>>>>..>>>>.
>>....<<<<<<....>>>>>>.......>>>>>....>>>.>>>.....
>>>>>>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<.....
.<<.....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>..
....<....<<<<<<..........>>>>>>....>.....>>>>>....
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
.....<<.<..<<<<.<<....<<<<<<<<.<<<..<<.<..<...<<<<
<<<.<<<.<<<<<....>>>>>.>>>.>>>>>>>...>..>.>>..>>>.
>>>>>>>>...>>.>>>>...>.>>.........<<<<<<<<<....>>>
>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7olc High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
V3 K7 L9 K11 K13 K18 K27 R115 K116 W117 L120 R136 R146 N148 Q149 K151 Y155 Q157 S158 S159 R165 K199 G203 K216
Binding residue
(residue number reindexed from 1)
V1 K5 L7 K9 K11 K16 K25 R113 K114 W115 L118 R134 R144 N146 Q147 K149 Y153 Q155 S156 S157 R163 K197 G201 K214
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7olc, PDBe:7olc, PDBj:7olc
PDBsum7olc
PubMed35079002
UniProtG0S7T8

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