Structure of PDB 7qca Chain SAA Binding Site BS01

Receptor Information

>7qca Chain SAA (length=101) Species: 1358809 (Spraguea lophii 42_110)

TKKRSNNGRSKKNRGHTRCVRCEHCSAMVPNDKAIKKFVVRSVIDAASLD
DLKIATIYEEYEVPKSYYKLNYCVSCAVHIKLVRVRSRWERKIRKEQRVS
A

Ligand information

>7qca Chain S60 (length=1354)

accagguugauucugccugacguggaugcuagucucauagauuuagccau
gcauguguaagcgaagcgauuagugaagcggcggaaggcucaguaacggg
cgaguauuuaaucucuagaaccggacaaccucaggaaacagaggggaaaa
cggaguaagagcauguguuagcaugugaugagaacaacagugcaggagag
uaagaagccaucccaucaguuaguaaguaggguaagggccuauuuagacg
uagacggguacgggggauuaggguuugauuccggagagggagccugagag
acggcuaccagguccaaggacagcagcaggcgcgaaaauuaccgaagccu
ccaagagggcgguagugaagagacgugaaaacaaguguguguaaaaacca
caugaguaacuggaggucaaggcuggugccagcauccgcgguaauaccag
cuccaggagugucuaugaugauugcugcgauuaaaagguccguagucgaa
gaacaguacuuguuuguaauguggcuuaucgagagccgaauagaacgaga
agaguucagaguaaggagcgaaggagggcuagauuauugagcagcgagag
gugaaauuugaugaccugcuuaggaguaacagaggcgaaagcgcuaguca
agaacgaauccgaugaucaaggacguaggcuggaggaucgaagacgauua
gagaccguaguaguuccagcaguaaacgaugccuacgcuguugugguuau
gagcacggcagaagagaaaucuaguagggcuuuggggagaguacgcgcgc
aagcgauaaauuuaaaggaaauugacggaagaacaccacaaggaguggag
ugugcggcuuaauuugacucaacgcgggacagcuuaccauacccgauggc
cgugugagcguaguacgcgauaggucagagaguggugcauggccguuaac
gacgaguggggugaccuuuggguuaaguccgcgaaguagugagaucccua
ggauacgaaaguuaucgacagguguuaaaaacacaggaaggaaggggcaa
gaacaggucagugaugcccuuagaugguaugggcugcacgcgcacuacag
uggucacagcagaaacaaauagaaguaaaugugaucgagagggaaugagc
acuguaaugugcacaggaacgaggaauugcuaguaaucguuaucucauua
agaagcgaugaaugugucccuguucuuuguacacaccgcccgucguuauc
gaagauggaaccaggugcgaacaagugaaagcgagugagugcaggguucu
agaucugauacaagucguaacaaggcagcuguaggagaaccuguagcugg
auca

..<<<<<.[.(((.>>>>>.<<<<<<<<<..<<<<<.<.......<<<.<
<<..<<....<<...<<.....>>...>>.>>......<<.......<<<
<.....<<...<<<<<.<..<<<.....<<<<.<....>.>>>>......
>>>....<..<<<<<<....>>>>>>..>....<<....>>.>.>>>>>.
.>>...>>>.><<<....<<<..<<<<<<<<.......>>>>>>>>>>>.
.....>>>..<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>..<<<<..>>>>....>>>>>>.........<<<....<<<
<...>>>>..>>>...>..>>>>>..........<<<<<.........>>
>>>......<<<<<((....<.<<<<.....<<..))>>.......>>>>
>>>>>>..>>>>>>>>>..........<<<((.....<<<<...<<<...
<<<<....<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>.
...>>>>.......<<<.<<......<<<<<<..<.<<<<<<<<...<<<
......>>>......>>>>>>>>..>........<<....>>.>>>>>>.
....>>..>>>...>>>...>>>>..<.<<<<<<<...<....<<<....
.....>>>....>>>>>>>>..>.......<<<.<<.<<<<<<<<.<<..
>>.>>>>>>>>..<<..))>>..>>..>>>.>>>.<<<.......<<<..
..>>>.....>>>....))).]<<<<<.<<<<<<<..<<.<<.<<<..<<
<<<<<<<<......<<........>>..........<<<<<<<...<<<<
<......<<<<...>>>>....>>>>>..<<<.<<<..<<.<<<<<<...
.<<.<..<<<....>>>...<<......>>......>.>>....<<<<<.
<..<<<....>>.>.>.....<<<<.....>>>>........>>>>>...
.>>>.>>>.....>>>>>>>>....>>>>>>>...>>.>>>>>>>>....
.<<<<<<<.....................>>>>>>>....<....<<.<<
<<......>>>>.>>....>.....>>>.>>....<<<<<..<<......
.>>.>>>>>......>>...>>>>>>>>>>.>>.......<<.<..<<<<
<.<...<<<<<<..<<<<..<<..<<....>>..>>..>>>>..>>>>>>
...>.>>>>>...>.>>.........<<<<<<<<<....>>>>>>>>>..
....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qca Spraguea lophii ribosome
• Resolution: 2.79 Å
• Binding residue (original residue number in PDB): T2 K3 K4 R5 S6 N7 N8 R10 K13 N14 R15 G16 H17 R19 K34 K70 V75 S76 K82 R85 V86 R87 S88 R89 W90 R92 R95 K96
• Binding residue (residue number reindexed from 1): T1 K2 K3 R4 S5 N6 N7 R9 K12 N13 R14 G15 H16 R18 K33 K69 V74 S75 K81 R84 V85 R86 S87 R88 W89 R91 R94 K95

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qca, PDBe:7qca, PDBj:7qca
• PDBsum: 7qca
• UniProt: S7W9M7