Structure of PDB 6x89 Chain S7 Binding Site BS01

Receptor Information

>6x89 Chain S7 (length=158) Species: 157791 (Vigna radiata)

VSKAAEFVISKVDDLMNWARRGSIWPMTFGLACCAVEMMHTGAARYDLDR
FGIIFRPSPRQSDCMIVAGTLTNKMAPALRKVYDQMPEPRWVISMGSCAN
GGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGLLQLQKKINRRK
DFLHWWTK

Ligand information

• Ligand ID: SF4
• InChI: InChI=1S/4Fe.4S
• InChIKey: LJBDFODJNLIPKO-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 2.0.7: [S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
  CACTVS 3.385: S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
• Formula: Fe4 S4
• Name: IRON/SULFUR CLUSTER
• PDB chain: 6x89 Chain S7 Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6x89 Atomic structure of a mitochondrial complex I intermediate from vascular plants.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): A87 C88 C89 G124 T125 C153
• Binding residue (residue number reindexed from 1): A32 C33 C34 G69 T70 C98
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0008137 NADH dehydrogenase (ubiquinone) activity
• GO:0046872 metal ion binding
• GO:0048038 quinone binding
• GO:0051536 iron-sulfur cluster binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0009060 aerobic respiration
• GO:0015990 electron transport coupled proton transport
• GO:0032981 mitochondrial respiratory chain complex I assembly

Cellular Component

• GO:0005739 mitochondrion

External links

• PDB: RCSB:6x89, PDBe:6x89, PDBj:6x89
• PDBsum: 6x89
• PubMed: 32840211
• UniProt: A0A1S3U8J5