Structure of PDB 8esw Chain S6 Binding Site BS01

Receptor Information
>8esw Chain S6 (length=90) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CRGDIEKVTHTGQVFDKEDYRNARFVNAKRYVNENWGIKLIEEVPPKECT
ERVVFCDGGDGPLGHPKVYINLDKPGNHICGYCGLRFVKK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8esw Chain S6 Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8esw Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		C87 H96 C111 C114
Binding residue
(residue number reindexed from 1)		C56 H65 C80 C83
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8esw, PDBe:8esw, PDBj:8esw
PDBsum8esw
PubMed36952377
UniProtQ9VMU0

[Back to BioLiP]