Structure of PDB 8hky Chain S27A Binding Site BS01

Receptor Information

>8hky Chain S27A (length=54) Species: 330779 (Sulfolobus acidocaldarius DSM 639)

QSKAVVRTYYEVEQDSIKLKNKKCPRCGSIMAHHMKPLERWACGKCGYTE
FIGK

Ligand information

>8hky Chain A16S (length=1493)

auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucgaaagggggagccaauccuuaaa
cccugccgcaguugggaucgagggcugaaacccgcccucgugaacgagga
aucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcucc
uugcacacaccgcccgucgcuccacccgagcgagaaaggggugagguccc
uugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucg
uaacaagguagccguaggggaaccugcggcuggaucaccucau

...<<<<..[.((((.>>>>.<<<<<<<<......<<<.<<......<<<
.<<<..<<<....<<<<<<......>>>>>>..>>>......<<<.....
..<<.<<<<..<<...<<<<<<<..<<<<....<<<<<......>>>>>.
....>>>>....<<<<<<<<..<<......>>.>>>>>>>>......<<<
<<<..............>>>>>>..>>>>>>>..>>>>>>.>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>>>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
.>....<<<<<((......<<<<......<..))>........>>>>.>>
>>>...>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<<..
....>>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<......
...>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.
<<<<<<.<<<<.<<<<<<......<<........>>..........<<<<
<.....<<<<........<<<.<<<.......>>>.>>>......>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<.<<....>>...<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<.<<.......<<<<....>>
>>.......>>>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>......>>>>>...>>.>>>>.>>>.>.
..<<.<<<<......<<..<<..<<<......>>>..>>....>>.....
>>>>.>>...........<<<<<<<........>>>>>>>..........
>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<
<.<<.....>>.>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>
...>.....<<<<<<<<<....>>>>>>>>>............

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8hky Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
• Resolution: 4.45 Å
• Binding residue (original residue number in PDB): Q12 S13 K14 V16 V17 R18 T19 Y21 E22 V23 E24 Q25 D26 S27 K29 K47
• Binding residue (residue number reindexed from 1): Q1 S2 K3 V5 V6 R7 T8 Y10 E11 V12 E13 Q14 D15 S16 K18 K36

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:8hky, PDBe:8hky, PDBj:8hky
• PDBsum: 8hky
• PubMed: 37604686
• UniProt: Q4JAG0|RS27A_SULAC Small ribosomal subunit protein eS31 (Gene Name=rps27ae)