Structure of PDB 8hl5 Chain S24E Binding Site BS01

Receptor Information

>8hl5 Chain S24E (length=96) Species: 330779 (Sulfolobus acidocaldarius DSM 639)

VSDKVEGIVERDIQNNVANRRELYIKLFHIGSGTPSRKELVKAIASTFST
AEDLVVVKKVFTNYGSGISYARVNVYKDKDSLQKLEPQYLIGRDTG

Ligand information

>8hl5 Chain A16S (length=1492)

auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucaaagggggagccaauccuuaaac
ccugccgcaguugggaucgagggcugaaacccgcccucgugaacgaggaa
ucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcuccu
ugcacacaccgcccgucgcuccacccgagcgagaaaggggugaggucccu
ugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucgu
aacaagguagccguaggggaaccugcggcuggaucaccucau

...<<<<....((((.>>>>.<<<<<<<<......<<<.<<......<<<
.<<<..<<<...<<<<<<<......>>>>>>>.>>>......<<......
..<<<<<<...<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>....<.<<<
<<<<<..........>>>>>>>>>.>>>>>>>..>>.>>>>>>.<<<...
.<<....<<<<<<<.......>>>>>>>..>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>...>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<....<<<..
....>>>.......>>>>>>>..>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<......
...>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..))))..<<<<<.<<<<<<<..<<.
<<<<<..<<<<<<<<<........<<........>>..........<<<<
<.<...<<<<<.......<<<.<<<.......>>>.>>>....>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<.<<....>>...<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<...<..<<.<<<<<....>>
>>>.>>>....>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>......>>>>>>>>.>.
..<<<<<<<.....<<...<<..<<<.....>>>..>>....>>.....>
>>>>>>...........<<<<<<<........>>>>>>>...........
>>>>>....<<<<<<<.........>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<<
<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>.
..>.....<<<<<<<<<....>>>>>>>>>............

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8hl5 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
• Resolution: 5.72 Å
• Binding residue (original residue number in PDB): G39 S40 G41 T42 P43 S44 R45 K67 V68 N71 Y72 Y97 R101
• Binding residue (residue number reindexed from 1): G31 S32 G33 T34 P35 S36 R37 K59 V60 N63 Y64 Y89 R93

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:8hl5, PDBe:8hl5, PDBj:8hl5
• PDBsum: 8hl5
• PubMed: 37604686
• UniProt: Q4JAF9|RS24_SULAC Small ribosomal subunit protein eS24 (Gene Name=rps24e)