Structure of PDB 7oyb Chain S2 Binding Site BS01

Receptor Information
>7oyb Chain S2 (length=136) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLNKR
AGELTEDEVERVVTIMQNPRQYKIPDWFLNRQKDIKDGKYSQVLANGLDN
KLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGR
Ligand information
>7oyb Chain 22 (length=1502) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguaauauaugcuugucucaaagauuaagcca
ugcaagucuaagugcacacgagugaaacugcgaauggcucauuaaaucag
uuaugguuccuuugaucacuuggauaacuguggcaauuccagagcuaaua
caugcgccgcgugcauuuaucaguggugacucuagauaacgccgaucgcg
cgcgcggcgacgguucauucgaaugucugcccuaucaacuuucgauggua
gguccgucgccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccauuuccgacacggagagguagugacgaaaaauaa
caauuuggaaugagugcaucccaaacccaugggcgaggacccauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaugc
uaacguugcugcaguuaaaaagcucguaguuggaucucuuuacuuugaaa
aaauuagaguguucaaggcagggccccccauugaauaccccagcuaggaa
uaauggaauaggaccccggggccaugaucgagagggacggccgggggcau
ucguauugcgccgcuagaggugaaauucuuggaccggcgcaagacggacc
ggagcgaaagcguuugccaagaacguuuucauuaaucaagaacgaaaguc
ggagguucgaagacgaucagauaccgucguaguuccgaccguaaacgaug
ccgacccgcgauccggcggcguuugacccgccgggcagcguugcgggaaa
ccacgagucucugggcuccggggggaguaugguugcaaagcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcuuaauuu
gacucaacacggggaaccucacccggcccggacaauugacagauucucga
uucugugggugguggugcauggccguucguaguugguggagcgauuuguc
ugguugauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcg
gccggucggcguaacuucuuagagggacaaguggcguucagccacgcgag
acugagcaauaacaggucugugaugcccuuagauguccggggcugcacgc
gcgccacaaugggcggaucaacguguccugcgccgacaggcgcggguaac
ccguugaaccccgcccgugauggggaccgauugaaacuauuucccgagaa
cgaggaauucccaguaagcgcaggucaucagcuugcguugauuaaguccc
ugcccuuuguacacaccgcccgucgcuacuaccgauugagcggcucagug
agguccucggaucggcgccgagaagacgaucgaacucggucguuuagagg
aaguaaaagucguaacaagguuuccguaggugaaccugcggaaggaucau
ua
...<<<<<.[.((((>>>>><<.<<<<<<<...<.<<..<......<<<.
<<<..<<....<<.............>>.>>......<<........<<<
.<<<..<<....<..<....<<.....<<.<<<.....>>>.>>......
>>..............<<<<<...<......>..>>>>>......<<<..
<....>.>>>..>...>...>>>>>.>>>.<<<....<<<.....<<<<<
<<.......>>>>>>>.>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>
>>>.........<<<....<<<.....>>>..>>>..>...>>.>.....
<<...>>......<<.<<<.........>>>.>>.........<.<<<((
......<<<......<<..))>>........>>>.>>>.>..>>>>>>>.
>>.........<.<((.....<.<<...<<<.<<.....<<<<<<.<...
....<<...<.......>...<<...>>.......>>......>.>>>..
>>>..........<<<..>>>......>>....<<<<<<..<...<<<<.
.<<..<<<<<<<<...<<<......>>>......>>>>>>>.>.>>....
...<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.........>>>>...>>>>>>>>..........<
<<.<<.<<<..<<<<<<<<.<<<.>>>>>>>>>>>..>>>....<<..))
>>....>>.....>>>.>.>.<<<......<<<......>>>....>>>.
.)))).]<<<<<.<<<<<<<..<<..<<<<<....<<............<
<........>>..........<<.<<...........<<.....>>....
........<.<..<<<..<<.<<<<<<....<<<.<<<<<....>>>...
<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<..<<<
<<..>>>.>>..>>>>..>>>>..>.....<<<<<.....>>>>>.....
...>>>....>>>.>>>.....>>>>>.>>......>>.>>.........
>.>.......<<<<<<........<.<<<<<<<<....>>>>>>>>....
>.........>>>>>>............<<..........>>........
......>>>>>.....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<.<<...<<<<..>>>>...>>.>>>>..>>>.>>>>>>>>...>>
.>>>>...>.>>.........<<<<<<<<<<..>>>>>>>>>>.......
..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oyb A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
K25 F28 K34 G35 V36 G37 R38 R39 Y40 W82 F83 L84 N85 H120 R121 H125 R130 V131 R132 G133 Q134 H135 T136 K137 T138 T139 R141
Binding residue
(residue number reindexed from 1)
K20 F23 K29 G30 V31 G32 R33 R34 Y35 W77 F78 L79 N80 H115 R116 H120 R125 V126 R127 G128 Q129 H130 T131 K132 T133 T134 R136
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7oyb, PDBe:7oyb, PDBj:7oyb
PDBsum7oyb
PubMed36653451
UniProtQ8JGS9|RS18_DANRE Small ribosomal subunit protein uS13 (Gene Name=rps18)

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