Structure of PDB 8hkz Chain S19P Binding Site BS01

Receptor Information
>8hkz Chain S19P (length=115) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WKKFRYRGKSLEDLLNMPMDEFIKLLPSRQRRSLKRGFSDKQRRLLEKIR
KISREGKQNKVIKTHVRNMVILPEMVGLRFAVYNGKEFVEFQVVPEMIGR
YLGEYSITTKKVEHG
Ligand information
>8hkz Chain A16S (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucgaaagggggagccaauccuuaaa
cccugccgcaguugggaucgagggcugaaacccgcccucgugaacgagga
aucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcucc
uugcacacaccgcccgucgcuccacccgagcgagaaaggggugagguccc
uugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucg
uaacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<<.[.((((>>>>>.<<<<<<<<<.....<<<.<<......<<<
.<<<..<<<..<<<<<<<<......>>>>>>>>>>>......<<......
..<<<<<<...<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<<<<..<<......>>.>>>>>>>>.....<<<<
<<<..............>>>>>>>.>>>>>>>..>>.>>>>>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<<..
....>>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<......
...>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.
<<<<<<.<<<<<<<<<<<......<<........>>..........<<<<
<.....<<<<<.......<<<.<<<.......>>>.>>>....>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<..........<<<<....>>
>>.........>>>>>>.>....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>......>>>>>...>>.>>>>>>>>.>.
..<<.<<<<.....<<...<<..<<<<....>>>>..>>....>>.....
>>>>.>>...........<<<<<<<........>>>>>>>..........
>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<
<<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>
...>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hkz Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Resolution4.78 Å
Binding residue
(original residue number in PDB)
P35 S36 R37 R39 S41 R44 G45 K49 K56 I70 K71 T72 H73 R75 N76 Y91 G93 K94 Y109 E112 S114 T116 T117 K119 V120 H122
Binding residue
(residue number reindexed from 1)
P27 S28 R29 R31 S33 R36 G37 K41 K48 I62 K63 T64 H65 R67 N68 Y83 G85 K86 Y101 E104 S106 T108 T109 K111 V112 H114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8hkz, PDBe:8hkz, PDBj:8hkz
PDBsum8hkz
PubMed37604686
UniProtQ4JB44|RS19_SULAC Small ribosomal subunit protein uS19 (Gene Name=rps19)

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