Structure of PDB 8hl1 Chain S19E Binding Site BS01

Receptor Information
>8hl1 Chain S19E (length=149) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVQMVPADILIPKLAEYLKNNVKELNPPNWVYFAKTASFKERVPDDIENW
WYIRAASLLRHLYIYKEPIGLQKTRKLYSGSKRRGTKPPRSVAPTHSIRT
ILQQLEKAGLVTKTRRGRILSPKGRSLLDKLAYEMFKELAEKKQDLKKY
Ligand information
>8hl1 Chain A16S (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucgaaagggggagccaauccuuaaa
cccugccgcaguugggaucgagggcugaaacccgcccucgugaacgagga
aucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcucc
uugcacacaccgcccgucgcuccacccgagcgagaaaggggugagguccc
uugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucg
uaacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<<.[.((((>>>>>.<<<<<<<<<.....<<<.<<......<<<
.<<<..<<<..<<<<<<<<......>>>>>>>>>>>......<<......
..<<<<<<<..<<...<<<<<<<.<<<<<...<<<<<<......>>>>>.
>...>>>>>..<<<<<<<<<<.<<......>>>>>>>>>>>>...<<.<<
<<<<............>>>>>>>>.>>>>>>>..>>>>>>>>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<<..
>>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<..<.<<<..
....>>>......>>>>>>>>..>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<....
.>.>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.
<<<<<<..<<<<<<<<.<......<<........>>..........<<<<
<.<...<<<<<<......<<<.<<<.......>>>.>>>...>>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<.<.....<<<<<<<....>>
>>>>>.....>>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>...>..>>>>>>>>...
..<<<<<<<.....<<...<<..<<<......>>>..>>....>>.....
>>>>>>>......<....<<<<<<<........>>>>>>>....>.....
>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<
<<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>
...>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB8hl1 Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Resolution3.93 Å
Binding residue
(original residue number in PDB)		W31 A38 I48 R55 S58 H62 L72 Q73 K74 Y79 K83 R84 P89 P90 R91 S92 V93 A95 P96 R101 Q105 R117 R118 G119 R120 R127 S128 D131 Y135 F138 K139 A142
Binding residue
(residue number reindexed from 1)		W30 A37 I47 R54 S57 H61 L71 Q72 K73 Y78 K82 R83 P88 P89 R90 S91 V92 A93 P94 R99 Q103 R115 R116 G117 R118 R125 S126 D129 Y133 F136 K137 A140
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8hl1, PDBe:8hl1, PDBj:8hl1
PDBsum8hl1
PubMed37604686
UniProtQ4J8U1

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