Structure of PDB 8hl3 Chain S15P Binding Site BS01

Receptor Information
>8hl3 Chain S15P (length=149) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNKKRAKGNSHSIRPVRSGPPKWVRFTREEVELLVEELAKRGYPPSMIGM
VLRDQYGVPLVKQITGRKLTAILQDRNMKPKIPEDLFNLMRRAVNIRRHL
FEYPKDKSAKRGLEEVESKIRRLASYYKETGKLPQEWSYDPAKAELLVT
Ligand information
>8hl3 Chain A16S (length=1492) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucaaagggggagccaauccuuaaac
ccugccgcaguugggaucgagggcugaaacccgcccucgugaacgaggaa
ucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcuccu
ugcacacaccgcccgucgcuccacccgagcgagaaaggggugaggucccu
ugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucgu
aacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<<.[.((((>>>>>.<<<<<<<<<<....<<<.<<......<<<
.<<<..<<<..<<<<<<<<......>>>>>>>>>>>......<<......
..<<.<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>....<.<<<
<<<<............>>>>>>>>.>>>>>>>..>>>>>>.>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>.>>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<<..
....>>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<....
.>.>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]..<<<.<<<<<<<..<<.
<<<<<<..<<<<<<<<<<......<<........>>..........<<<<
<.<...<<<<<<......<<<.<<<.......>>>.>>>...>>.>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<.<<....>>...<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<..<<..<<.<<<<<....>>
>>>.>>>>...>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>...>>.>>>>>>>>...
..<<<<<<<.....<<...<<<.<<<.....>>>.>>>....>>.....>
>>>>>>......<....<<<<<<<........>>>>>>>....>.....>
>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>
>>>.......<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<<
<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>.
..>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hl3 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution4.8 Å
Binding residue
(original residue number in PDB)		M1 K3 K4 R5 A6 G8 N9 S10 H11 S12 I13 R14 P45 S46 M50 R53 K68 L69 T70 D85 N88 R92 R98 H99 Y103 K105 D106 K107 S108 K110 R111 K119 R122 Y126
Binding residue
(residue number reindexed from 1)		M1 K3 K4 R5 A6 G8 N9 S10 H11 S12 I13 R14 P45 S46 M50 R53 K68 L69 T70 D85 N88 R92 R98 H99 Y103 K105 D106 K107 S108 K110 R111 K119 R122 Y126
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hl3, PDBe:8hl3, PDBj:8hl3
PDBsum8hl3
PubMed37604686
UniProtQ4JAI3|RS15_SULAC Small ribosomal subunit protein uS15 (Gene Name=rps15)

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