Structure of PDB 7qep Chain S1 Binding Site BS01

Receptor Information

>7qep Chain S1 (length=209) Species: 284813 (Encephalitozoon cuniculi GB-M1)

AIQPPGSYPNAFARKEWYTLRSPSIFPNNINGKTLMTKSAGKNSYMNMIG
RRYDVNQADLTGNNDVGHRKFIFKIGDIKGSECVGFFDGMELTSDKHKAM
IKKWHTLIEAQKDIVAKDGSVFRVFVMGVTRRHPGYVKKTCYVKHSDEKK
IRKIMFDVIEEELSGCDVQKIMKKLANETVGKRIEELGSEIFPLQNCCVR
KVKTIKSHQ

Ligand information

>7qep Chain 3 (length=1295)

aucagguugauucugccugacguggaugcuauucucuggggcuaagccau
gcaugcuugugaacucuuugugggggauuagcggacggcucagugauagc
acgaugauuuguuugcgggaugagcaguagcugcgggaaacugcagauag
uggucugccccuguggggguuggcaaguaaguugugggccuaucagcugg
uaguuaggguaauggccuaacuaggcgcagacgggauacgggggaucagg
guuugguuccggagagggagccugagagauggcuacuacguccaaggaug
gcagcaggcgcgaaacuugccuaauccuuuggggaggcgguuaugagaag
ugaugugugugcgagugcaaaggggucgcaugugauuggagggcaagucg
ggugccagcagccgcgguaauaccugcuccaauagugucuaugguggaug
cugcaguuaaaauguccguagucuguguaugucuuugugugugauguuug
ugguuguguguggauguagugaguguguggcagaggacgaggggcacugg
auaguugggcgagaggugaaaugcgaagacccugacuggacgagcggaag
cgaaggcugugcucuuggacuaauguugcgaugaaggacgaaggcuagag
gaucgaaaucgauuagauaccguuuuaguucuagcaguaaacgaugccga
cuggacgggacaguguguguuguccaugagaaaucuugaguaugcggguu
cuggggauaguaugcucgcaagagugaaacuugaagagauugacggaagg
acaccacaaggaguggagugugcggcuuaauuugacucaacgcggggcaa
cuuaccggcucugaaggaugccugugagugcauggcaugaggcaugcggc
gguggugcauggccguuuuaaauggauggcgugagcuuugucuuaaguug
cguaagaugugagacccuuugacgguguucuacggagcaaggaggggaug
gaagagaacagguccguuaugcccugagaugaggcgggcugcacgcgcac
uacgauagauggcgcuucugccugcugugagggaugaagcuguguaaggg
gcuucugaacguggaauuccuaguaauagcggcugacgaagcugcuuuga
augugucccuguccuuuguacacaccgcccgucgcuaucuaagaugacgc
acuggacgaagaucggaaggucugaguccugaguguuagauaagauauaa
gucguaacauggcugcuguuggagaaccagcagcaggaucaguau

..<<<<..[.((((.>>>>.<<<<<<<<<..<<<<<.<.......<<<.<
<<..<<<......<<<.....>>>.....>>>......<<.........<
<<<<<..<<..<<<<<.....<<.<<...<<<<<<......>>>>>.>..
>>.>>.<<<<<....>>>>>..>>>>>.>>>>>>>>..<<<....<<<..
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<<<<<<....
>>>>...>>>>.>>.<<.<<<..........>>>.>>.<<<<....>>>>
...>>>>>>.........<<<....<<....>>..>>>...>..>>>>>.
........<<<<<<.<.......>.>>>>>>....<<<<<((......<<
<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>.......
...<<<((.....<<<<...<<<....<<<<<<<....<<<<<<<.....
..>>>>>>>..>>>>>>>...........<<<.<<..<<.<<<<<<<<.<
.<<<<<<<<...<..........>......>>>>>>>>..>>.......<
<....>>.>>>>>>>>>..>>..>>>...>>>...>>>>....<<<<<<<
...<..<<.<<.<.....>.>>.>>..>>>>>>>>..........<<<.<
<.<<<<<<.<<<...>>>.>>>>>>..<<..))>>....>>.....>>>.
>>>.<<.......<<<<....>>>>.....>>..)))).]<<<<<.<<<<
<<<..<<.<<<<<<..<<<<<<<<<<......<<........>>......
....<<<.<<<......<<<<<.....<<<.....>>>..>>>>>....<
<<.<<<..<<.<<<<<<....<<<...<<<....>>>..<<........>
>......>>>.....<<........<<<<<....>>>>>..........>
>.....>>>.>>>.....>>>>>>>>....>>>.>>>...>>.>>>>>>>
>.....<<..<<<......>>>..>>....<....<<<<<<........>
>>>>>....>.....>>>>>>....<.<<<<<<.......>>>>>>.>..
....>>...>>>>>>>>>>.>>....<..<<.<..<<<<<.<...<<<<<
.<.<<<<..<<<<<....>>>>>..>>>>.>.>>>>>...>.>>>>>...
>.>>...>.....<<<<<<<<<....>>>>>>>>>..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qep Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): Q4 Y9 P10 R67 K89 I116 K117 K118 W119 Y157 K159 H160 S161 R167 K216 K218
• Binding residue (residue number reindexed from 1): Q3 Y8 P9 R52 K74 I101 K102 K103 W104 Y142 K144 H145 S146 R152 K201 K203

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qep, PDBe:7qep, PDBj:7qep
• PDBsum: 7qep
• UniProt: Q8SS05|RS3A_ENCCU Small ribosomal subunit protein eS1 (Gene Name=RPS1)