Structure of PDB 8u5h Chain S Binding Site BS01

Receptor Information
>8u5h Chain S (length=96) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASR
LAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>8u5h Chain C (length=157) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgtaaacatcctggagaatcccggtgccgaggccgctcaattggtcgta
gacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtttt
aaccgccaaggggattactccctagtctccaggcacgtgtcagatatata
catcctg
Receptor-Ligand Complex Structure
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PDB8u5h Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
Resolution3.23 Å
Binding residue
(original residue number in PDB)		T29 Y39 S53 R83 S84 T85
Binding residue
(residue number reindexed from 1)		T3 Y13 S27 R57 S58 T59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8u5h, PDBe:8u5h, PDBj:8u5h
PDBsum8u5h
PubMed
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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