Structure of PDB 8qu1 Chain S Binding Site BS01

Receptor Information
>8qu1 Chain S (length=156) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GYVPKTSLSSPPWPEVVLPDPVEETRHHAEVVKKVNEMIVTGQYGRLFAV
VHFASRQWKVTSEDLILIGNELDLACGERIRLEKVLLVGADNFTLLGKPL
LGKDLVRVEATVIEKTESWPRIIMRFRKRKNFKKKRIVTTPQTVLRINSI
EIAPCL
Ligand information
>8qu1 Chain A (length=938) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccaauaaaguauagg
cgauagaaauugggcgcaauagauauaguaccgcaagggaaagaugaaaa
auaccaagcauaauauagcaaggacuaaccccuauaccuucugaugaauu
aacuagaaauaacuuugcaaggagagccaaagcuaagacccccgaaacca
gacgaagccuggugauagcugguuguccaagauagacaacuuuaaauuug
cccacagaaccaaauccccuuguaaauuuaacuguuaguccaaagaggaa
cagcucuuuggacacuaggaaaaaaccuuguagagagaguaaaaaauuua
acacccauaguaggccuaaaagcagccaccaauuaagaaagcguucaagc
ucaacacucccaaacauauaacugaacuccucacacccaauuggaccaau
cuaucacccuauagaagaacuaauguuaguauaaguaacaugaaaacauu
cuccuccgcauaagccugcgucagaucacugacaauuaacagcccaauau
cuacaaucaaccaacaagucauuauuacccucacugucaacccaaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaaacaucaccucuagcau
caccaguauuagaggccagcugucucuuacuuuuaaccagugaaauugac
cugcccgugaggcgggcauaacacagcaagacgagacccuauggagcuuu
aauuuauuaaugcaaacaccugcauuaaaaauacaugcuaagacuucacc
agucaaagcgaacaguuacccuaggguaucuacuuuauuccucccuguac
gaaaggacaagagaaauaaggccuacuucacaaagcgccuucuaaaugau
aucaucucaacuuaauacccacacccaagaacaggguu
<<<.......<<<<................................<<..
...>>.......>>.>>.............<<....>>............
......>>>...........<<<.......>>>...<.<....>.>.<<<
<<<.........<<<.<<..<<....>>...>>.>>>...<<.<..<<<<
<.<...>.>>>>...>..>.>>..<<<<<<....<.><<<.<<<<<<<<<
<.....<<......>>.....>>>>>>>>>>..>>>.<<<<<<<<<<...
...>>>>>>>>>>...<<<......>>>....<<<.<<<...<.......
.......<....<<<.........>>>....>.......<<<......>>
>.....................>...>>>>>>........>>>>>>...<
<<<<......>>>>>.........>>>>>><......<<..<<<....>>
><<<<..<<<<........<<<<<....>>>>>......<<<...<<<<.
......................>>>>.......>>>.....<<..>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<.........<<<<<<....
.........>>>>>>........>>.>>>>>>>>>>>>.>>.....>...
..<<<<<.....>>>>>.......<<..<<<.....<<<<<.<<<<<<..
..<<..<<<<<<<<......>>>>>>>.>>>.....<<<..<<<<.....
>>>>..>>>....>>>>..>>>>>>>..>>>.>>..<<<.<<<.......
..........>>>.>>><<<<<...<<<....>>>.>>>>>.<<<.<...
.........>.>>>........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qu1 GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Resolution2.74 Å
Binding residue
(original residue number in PDB)		W61 P62 A102 S103 R104 N118 R169 R173 R175 K176 R177 F180 K182 R184
Binding residue
(residue number reindexed from 1)		W13 P14 A54 S55 R56 N70 R121 R125 R127 K128 R129 F132 K134 R136
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qu1, PDBe:8qu1, PDBj:8qu1
PDBsum8qu1
PubMed38969660
UniProtQ7Z2W9|RM21_HUMAN Large ribosomal subunit protein bL21m (Gene Name=MRPL21)

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