Structure of PDB 8q5i Chain S Binding Site BS01

Receptor Information
>8q5i Chain S (length=125) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRVRTKTVKRASKVLIERFYPKLTLDFETNKRLTSEIAVIQSKRLRNKIA
GYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSHTNGQLE
IDADTADLVKSLGFKIPVQTVSISA
Ligand information
>8q5i Chain A (length=1558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagagaugauucauaauaacuuuucgaaucgcauggccuugugcugg
cgaugguucauucaaauuucugcccuaucaacuuucgaugguaggauagu
ggccuaccaugguuucaacggguaacggggaauaaggguucgauuccgga
gagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcgc
aaauuacccaaucccgacacggggagguagugacaauaaauaacgauaca
gguuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauug
gagggcaagucuggugccagcagccgcgguaauuccagcuccaaaagcgu
auauuaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuugg
cugcagccgagccuuuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuauaucg
uaaugauuaauagggacggucggggguaucaguauucaguugucagaggu
gaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuaccaag
gacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugaucaga
uaccgucguagucuuaaccauaaacuaugccgacuagggaucgguuguug
uucugacgcaaucggcaccuuacgagaaaucaaagucuuuggguucuggg
gggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacc
accaggaguggagccugcggcuuaauuugacucaacacggggaaacucac
cagguccagacacugagagcugugggugguggugcauggccguucuuagu
ugguggagugauuugucugcuuaauugcgauaacgaacgagaccuuaacc
uacuaaauagugccacuucuuagagggacuaucgauuucaagucgaugga
aguuugaggcaauaacaggucugugaugcccuuagacguucugggccgca
cgcgcgcuacacugacggagccagcgaguauaagccuuggccgagagguc
ugggaaaucuugugaaacuccgucgugcuggggauagagcauuguaauug
uugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguu
gauuacgucccugcccuuuguacacaccgcccgucgcuacuaccgauuga
auggcuuagugaggccuccggauuggcgagaagcuggucaaacuugguca
uuuagaggaaguaaaagucguaacaagguuuccguaggugaaccugcgga
aggaucau
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<<<<<...........>>>>>>.....>...<<<<..<<<.....>>>.>
>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<.....
..>>>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.>
>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>....
.....<<<....<<<<...>>>>..>>>..>....>.>.....<<<<...
<..>...>>>>......<<..<...........>..>>.........<<<
<<((....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>
>>>>>>.........<<<((.....<.<<...<<<.<<....<<<<<<<<
<<..>>>>>>>>>>...<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<..>>>
>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<..
....>>>......>.>>>>>>..>>.......<<....>>...>>>>...
>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<....
.>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<..
<<..>>.>>>>>>>>..>>>...<<..))>>...>>.....>>>.>>>.<
<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..
<<.<<<<<<..<<<.<<<<.<......<<........>>..........<
<<<<.<....<<<........>>>...<<.<<<..<<.<<<<<<....<<
<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<
..<<<<..<<<<.>>>>..>>>>.>>....<<<<<<.....>>>>>>...
....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>..
>>>>.>>>.....<<<<<<<......<<......<<<.<<<<....>>>>
.>>>....>>.......>>>>>>>...........<<<<<<.........
.>>>>>>..........>>>>>>....<<<<<<<<.......>>>>>>>>
......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<
<<<<<<.<<<..<<<<..<...<<<.>>>...>..>>>>..>>>.>>>>>
>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>
>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q5i Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Resolution2.45 Å
Binding residue
(original residue number in PDB)
G2 R3 V4 R5 T6 K7 K10 R11 F28 K32 S43 K44 R45 N48 K49 H56 R60 R67
Binding residue
(residue number reindexed from 1)
G1 R2 V3 R4 T5 K6 K9 R10 F27 K31 S42 K43 R44 N47 K48 H55 R59 R66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8q5i, PDBe:8q5i, PDBj:8q5i
PDBsum8q5i
PubMed
UniProtA0A8H6BTR7

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