Structure of PDB 8kd6 Chain S Binding Site BS01

Receptor Information
>8kd6 Chain S (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQ
SSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>8kd6 Chain X (length=164) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcggccgctctagaacaggatgtatatatctgacacgtgcctggagact
agggagtaatccccttggcggttaaaacgcgggggacagcgcgtacgtgc
gtttaagcggtgctagagctgtctacgaccaattgagcggcctcggcacc
gggattctccaggg
Receptor-Ligand Complex Structure
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PDB8kd6 Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
Resolution3.07 Å
Binding residue
(original residue number in PDB)
R40 R42 R72 F84 Q85 R116 V117
Binding residue
(residue number reindexed from 1)
R5 R7 R37 F49 Q50 R81 V82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8kd6, PDBe:8kd6, PDBj:8kd6
PDBsum8kd6
PubMed37666978
UniProtP84233|H32_XENLA Histone H3.2

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