Structure of PDB 8euy Chain S Binding Site BS01

Receptor Information
>8euy Chain S (length=168) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALKEYQVVGRKVPTEHEPVPKLFRMRLFAPNESVAKSRYWYFLKMINKVK
KATGEIVAINEISEPKPLKAKVFGIWIRYDSRSGTHNMYKEFRDTTRVGA
VEAMYADMAARHRARFRSIRILKVVEVEKKEDVRRNYVKQLLNPHLKFPL
PHRRTKKVFAPHRPSTFY
Ligand information
>8euy Chain 1 (length=1433) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggagugaagcgggaaaagcucaa
auuugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaaga
agcugcuuugaguguagacgaucggucuaaguuccuuggaacaggacguc
agagagggugagaaccccgucuuuggucgauuggauaugccauauaaagc
gcuuucgaagagucgaguuguuugcagcucuaaaugggugguaucaucua
aagcuaaauauuggcgagagaccgauagcgaacaaguagagugaucgaaa
gaugaaaagaacuuugaaaagagaguuaaauaguacgugaaauugcugaa
agggaagcauuggaaaucagucuuaccugggugagaucaguagucucucg
agacuaugcacucugaaccugugguaggucagcaucaguuuucgggggcg
gaaaaagaauaagggaagguggcguguuuauagccuuguuguaauacguc
cacuggggacugaggacugcggcuucgugccaaggaugcugacauaaugg
uuuucaauggcccgucuugaaacacggaccaaggagucuagcaucuaugc
gaguguuugggugaugaaaacccauccgcgaagugggaacgcccuugugg
cgugcaccagagcauagcuguugggacccgaaagauggugagaaccaucu
aguagcugguuccugccgaaguuuccggauagcagaaacucagaucaguu
uuaugaguauguaaaaugagaguuucuagugggccauuuuugguaagcag
aacuggcgaugcgggaugaaccgaacgugagguuaaggugccggaaugua
cgcucaucagacgaaaagguguuaguucaugaacuagcccugggcgcuua
agcguacuacccauaccucaccgucuggguuagcuuugagaagcucagac
gaguaggcaggcguggagguuugugacgaagccuugggcgugagccuggg
ucgaacagccucuagugcagaucuugguggaaguagcucuagcgaaacca
cagccuggggaacgggccaggucgucgcaaugguaauucaacuuaguacg
agaggaaccguugauucagaucauugguauuugcgcggagcuaucaucug
cuggauaacggcugaacgccucuaagccagaauccgugccagaaagcgac
gagguccgcauauguauaaaaauagagguaggcuacucuccuguaucgua
gaagaugggcgaugguugaugaaacggaaguguuuuauugacuuguccau
gaaauuccaugugcggaaucgaauccauugcauacgacuuuaauguggaa
cgggguauugagauucuuuguucccaagauuug
........................<<<<<<........>>>>>.>.....
....<<....>>..<<<<<......<<...>>.....>>>>>..<<<..<
<.......<<.<<<<<<<.......>>>>>>>.>>.......>>....<<
<<<.<<<<<..<<<<<..<<<<<<<<<.....<<<<......>>>>.((.
.....<<<.....))>>>......>>>>>>>>>..>>>>>.....>>>>>
>>>.>>........<<<<<<<..>>>>>>>.....<<<<<<..>>>>>>.
.>>>..................................<<....>>....
...........<<<<....>>>>...........................
.......<<<<<<<<<<<<.....<<<.<<<<.<<<.<<.<<<<<<<..>
>>>>>>>>...>>>..>>>>..>>>..<<<<<<<.<<<<<<<<<<<<<<<
.......<<<<<<<.......<..>........>>>>>>>......>>>>
>.>>>>>>>>>>........<<<.....>>>.....>>>>>>>....>>>
>>>>>>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<
..<<<...<<<<.......>>>>...>>>...<<<....<<<....>>>.
....>>>....>>>>>>.>>>>>>..<<.<...<<<<<<....>>>>>>.
.....>.>>..<<<<<<....<.<<..>>.><<<<<<<<<<...<<<.<<
<<<<<....>>>>>>>>>>>>>>>>>>.>>..<<<<.<<<<<.....>>>
>>.>>>>....<<<......>>>...<<<<<<<...<<<(((.....<<<
<<<......<......<<<.<<<<<<<<..>>>>>>>>>>>.))).>...
.>>>>>>.>>>...>>>>>>><<<<<<<<<............>>>>>>>>
>....>>>>>><.<<<<<<<..<<......<<<<.<<<<....>>>>>>>
>...>>.>>>>>>>..>.....>>>>>><<.....<<....>>....>>.
...<<<<<........>>>>><<<<<<<..<<<<.<.<<<<<........
.........>>>>>.><<<<<...<<<<....<..>...>>>>..>>>>>
.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>>>
>><.<<<<<<<....<<.......<<<<.<<.>>..>>>>....>>....
....<<<<<.....<<<<<<<<<<<......>>>>>>>>>>>...>>>>>
..........>>>>>>>.><<<<<<.....................<<<<
<<<...<<....>>..>>.>>>>>...>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8euy Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		N61 I63 S64 E65 P66 K67 P68 H87 N88 Y90 K91 A110 A111 R112 H113 R114 R136 L143 N144 P145 L147 H153 R155 P169 H170 R171 P172 S173 T174 F175 Y176
Binding residue
(residue number reindexed from 1)		N60 I62 S63 E64 P65 K66 P67 H86 N87 Y89 K90 A109 A110 R111 H112 R113 R135 L142 N143 P144 L146 H152 R154 P161 H162 R163 P164 S165 T166 F167 Y168
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8euy, PDBe:8euy, PDBj:8euy
PDBsum8euy
PubMed36423630
UniProtP0CT68|RL20A_SCHPO Large ribosomal subunit protein eL20A (Gene Name=rpl2001)

[Back to BioLiP]