Structure of PDB 8cst Chain S Binding Site BS01

Receptor Information
>8cst Chain S (length=133) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGSRLETVGSIFSRTRDLVRAGVLKEKPLWFDVYDAFPPLREPVFQRPRV
RYGKAKAPIQDIWYHEDRIRAKFYSVYGSGQRAFDLFNPNFKSTCQRFVE
KYTELQKLGETDEEKLFVETGKALLAEGVILRR
Ligand information
>8cst Chain A (length=888) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaacucaccugaguuguaaaaaacuccaguuga
cacaaaauagacuacgaaaguggcuuuaacauaucugaacacacaauagc
uaagacccaaacugggauuagauaccccacuaugcuuagcccuaaaccuc
aacaguuaaaucaacaaaacugcucgccagaacacuacgagccacagcuu
aaaacucaaaggaccuggcggugcuucauaucccucuagaggagccuguu
cuguaaucgauaaaccccgaucaaccucaccaccucuugcucagccuaua
uaccgccaucuaacccugaugaaggcuacaaaguacguuaggucaaggug
uagcccaugagguggcaagaaaugggcuacauuuucuaccccagaaaacu
acgauagcccuuaugaaacuuaagggucgaagguggauuuagcaguaaac
ugagaguagagugcuuaguugaacagggcccugaagcgcgucacccuccu
caaguauacuucaaaggacauuuaacuaaaaccccuacgcauuuauauag
aggagacaaguaaguguacuggaaagugcacuuggacg
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<....<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>.........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<......<<<.<<<.<<<......>>>..>>>.>>>
.............<<....>>.>>>>>>.....>>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<....>>>>
.....>>..>>>>>>......<<<<<<<...<<<.<<<<<..<<<<<<<<
.......<<........>>..........<<<<<<<.......<<.<<<.
.<<.<<<<.<..<<<<<.....>>>.......>>..>.>.>>>....>>>
>>>>....>>>>>>>.....>>>>>>>>.....<<<<.....>>>>....
.<....<<<<<<<.......>>>>>>>....>.....>>>>>.....<<<
<<<<.........>>>>>>>.....>>>...>>>>>>>.......<<<<<
<..<<<<<......<<<....<<.....>>...>>>.......>>>>>.>
>>>>>......<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cst Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.85 Å
Binding residue
(original residue number in PDB)
R5 R48 R50 Y53 K55
Binding residue
(residue number reindexed from 1)
R4 R47 R49 Y52 K54
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0031965 nuclear membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8cst, PDBe:8cst, PDBj:8cst
PDBsum8cst
PubMed36482135
UniProtQ9Y3D9|RT23_HUMAN Small ribosomal subunit protein mS23 (Gene Name=MRPS23)

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