Structure of PDB 7yla Chain S Binding Site BS01

Receptor Information
>7yla Chain S (length=122) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRG
KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIF
GPVTRELRSEKFMKIISLAPEV
Ligand information
>7yla Chain I (length=2876) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgau
gaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguu
auaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuau
cauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacau
cuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcg
agcgaacggggagcagcccagagccugaaucaguguguguguuaguggaa
gcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaug
cacaugcugugagcucgaugaguagggcgggacacgugguauccugucug
aauauggggggaccauccuccaaggcuaaauacuccugacugaccgauag
ugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagug
aaaaagaaccugaaaccguguacguacaagcagugggagcacgcugcgug
ugacugcguaccuuuuguauaaugggucagcgacuuauauucuguagcaa
gguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggcguu
aaguugcaggguauagacccgaaacccggugaucuagccaugggcagguu
gaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaaaaa
uuagcggaugacuuguggcugggggugaaaggccaaucaaaccgggagau
agcugguucuccccgaaagcuauuuagguagcgccucgugaauucaucuc
cggggguagagcacuguuucggcaagggggucacuuaccaacccgaugca
aacugcgaauaccggagaauguuaucacgggagacacacggcgggugcua
acguccgucgugaagagggaaacaacccagaccgccagcuaaggucccaa
agucaugguuaagugggaaacgaugugggaaggcccagacagccaggaug
uuggcaagcagccaucauuuaaagaaagcguaauagcucacuggucgagu
cggccugcgcggaagauguaacggggcuaaaccaugcaccgaagcugcgg
cagcgacgcuuaugcguuguuggguaggggagcguucuguaagccugcga
aggugugcugugaggcaugcuggagguaucagaagugcgaaugcugacau
aaguaacgauaaagcgggugaaaagcccgcucgccggaagaccaaggguu
ccuguccaacguuaaucggggcagggugagucgaccccuaaggcgaggcc
gaaaggcguagucgaugggaaacagguuaauauuccuguacuugguguua
cugcgaaggggggacggagaaggcuauguuggccgggcgacgguuguccc
gguuuaagcguguaggcugguuuuccaggcaaauccggaaaaucaaggcu
gaggcgugaugacgaggcacuacggugcugaagcaacaaaugcccugcuu
ccaggaaaagccucuaagcaucagguaacaucaaaucguaccccaaaccg
acacagguggucagguagagaauaccaaggcgcuugagagaacucgggug
aaggaacuaggcaaaauggugccguaacuucgggagaaggcacgcugaua
uguaggugaggucccucgcggauggagcugaaaucagucgaagauaccag
cuggcugcaacuguuuauuaaaaacacagcacugugcaaacacgaaagug
gacguauacggugugacgccugcccggugccggaagguuaauugaugggg
uuagcgcaagcgaagcucuugaucgaagccccgguaaacggcggccgguc
cuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaauggc
guaaugauggccaggcugucuccacccgagacucagugaaauugaacucg
cugugaagaugcaguguacccgcggcaagacggaaagaccccgugaaccu
uuacuauagcuugacacugaacauugagccuugauguguaggauaggugg
gaggcuuugaaguguggacgccagucugcauggagccgaccuugaaauac
cacccuuuaauguuugauguucuaacguugacccguaauccggguugcgg
acagugucugguggguaguuugacuggggcggucuccuccuaaagaguaa
cggaggagcacgaagguuggcuaauccuggucggacaucaggagguuagu
gcaauggcauaagccagcuugacugcgagcgugacggcgcgagcaggugc
gaaagcaggucauagugauccggugguucugaauggaagggccaucgcuc
aacggauaaaagguacuccggggauaacaggcugauaccgcccaagaguu
cauaucgacggcgguguuuggcaccucgaugucggcucaucacauccugg
ggcugaaguaggucccaaggguauggcuguucgccauuuaaagugguacg
cgagcuggguuuagaacgucgugagacaguucggucccuaucugccgugg
gcgcuggagaacugaggggggcugcuccuaguacgagaggaccggagugg
acgcaucacugguguucggguugucaugccaauggcacugcccgguagcu
aaaugcggaagagauaagugcugaaagcaucuaagcacgaaacuugcccc
gagaugaguucucccugacccuuuaaggguccugaaggaacguugaagac
gacgacguugauaggccggguguguaagcgcagcgaugcguugagcuaac
cgguacuaaugaaccgugaggcuuaa
..<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<...
...<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>...
...>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<<.....<<....
.>>....>>>>>>..(((..<<<<......<<<<<<<<<<<<<.<<<...
<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>
>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>.
.....<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]].....
..........<<....>>....]].........<<<<.....>>>>....
..............>>>>>>>>>>>.......<<<<..<<<<<<.>>>>>
>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..
<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>...
..>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<<
...<<<<<........>>>>>.>...>>>...<<<.<<<<<........>
>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>....
..>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<<<<
<<<.....<<<...<<<.<<<<...<<.<<<.>>>..>>...>>>>.>>>
..>>.>.....>>>>>>.>>>...>>>>>>>.>...<<<<<<<<<<....
..>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((..
...<<<<<<...........<<..<<<<<..<<........<<<<<.<<.
..<<.......>>...>>........<<<......>>>..>>>>>....>
>..>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>>
<<<<<<.<<....>>.>>>>>>....>>>>>>..<<<<<...<<<.....
.<<<<<<<<....>>>>>>>>...>>>..>>>>>........>>>>>><.
.....<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...
<<<<<<...<<.....>>.>>>>>>....((<<<.<<<...<<<...<<<
....>>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<
<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<....(((...>>>
>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>
...>>>>...>><..<<<<<....>>>>>...>>>>>>...>>>...>>>
>.........>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<.
.....>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<
.<<...............<<<<<....<<..>>.....>>>>><<<<<<.
....<<<...<<<<.....>>>>...>>>...>>>>>>............
<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>
.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<........<<<<
<<.<<....>>..>>>>>>........>>>>>>>>..>>>>><<<..>>>
........<...........<<<<<<.....>>>>>>.....>....>>>
>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<
<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<
..<<<<<.<<<.<<<<<.<<<<<<<<<<...<<............<<<<<
..<<<......<<<<<.<<....>>.>>>>>...>>>............>
>>>>...>>...>>>>>>>>>>...<<<.<<<<<<.....>>>>>>>>>.
...>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>.(<<...<<<<<<<...<<<<<<.......>>>>>>.....<<
)..(((>>....>>>>>>>...<<<<..<<<<....>>>>..>>>>.<<<
....>>>.>>))).......<<<<<<<.((..>>>>..))>>>>>>>...
..........>>>>..]]>>>>.......<<<<.<.<<<<<<...<<...
....>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<
<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>
...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>>>
>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>
.<<<<<...<<<<...<<<<<<<<<<<))).>>>>>>..>>>>>...>>>
>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>
.......>>>>>>>..<<<<<.....>>>>><....<<..<<<<<.....
..>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>...>
>>>>.>>>.....>>..>..>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yla Cryo-EM structure of 50S-HflX complex
Resolution2.52 Å
Binding residue
(original residue number in PDB)		M1 Q3 Q5 T6 M7 I22 K23 G26 S28 H29 R30 R31 Y32 K40 T42 K44 K54 V57 K66 K67 R70 N82
Binding residue
(residue number reindexed from 1)		M1 Q3 Q5 T6 M7 I22 K23 G26 S28 H29 R30 R31 Y32 K40 T42 K44 K54 V57 K66 K67 R70 N82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7yla, PDBe:7yla, PDBj:7yla
PDBsum7yla
PubMed
UniProtC3SQZ2

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