Structure of PDB 7c3f Chain S Binding Site BS01

Receptor Information
>7c3f Chain S (length=114) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTEPSEKSVEIMRKFSEQYARRSGTYFCVDKGVTSVVIKGLAEHKDSYGA
PLCPCRHYDDKAAEVGQGFWNCPCVPMRERKECHCMLFLTPDNDFAGKDQ
TITSDEIKETTANM
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7c3f Chain S Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7c3f Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity.
Resolution2.3986 Å
Binding residue
(original residue number in PDB)		C54 C73 C75 M78 C84 H85 C86
Binding residue
(residue number reindexed from 1)		C53 C72 C74 M77 C83 H84 C85
Annotation score1
Enzymatic activity
Enzyme Commision number 1.8.7.2: ferredoxin:thioredoxin reductase.
Gene Ontology
Molecular Function
GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors

View graph for
Molecular Function
External links
PDB RCSB:7c3f, PDBe:7c3f, PDBj:7c3f
PDBsum7c3f
PubMed33015914
UniProtQ9SJ89|FTRC_ARATH Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic (Gene Name=FTRC)

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