Structure of PDB 7asp Chain S Binding Site BS01

Receptor Information
>7asp Chain S (length=103) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLN
PEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEI
KSN
Ligand information
>7asp Chain Y (length=2723) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuauuaagggcgcacgguggaugccuuggcacuagaagccaauga
aggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuuga
uccagagauuuccgaauggggaaacccagcaugaguuaugucauguuauc
gauauguuagcauaucagaaggcacacccggagaacugaaacaucuuagu
acccggaggaagagaaagaaaauucgauucccuuaguagcggcgagcgaa
acgggaagagcccaaaccaacaaguugcuuguugggguuguaggacacuc
uaugaguuacaaaggacgacauuagacgaaucaucuggaaagaugaauca
aagaagguaauaauccuguagucgaaaauguugucucucuugaguggauc
cugaguacgacggagcacgugaaauuccgucggaaucugggaggaccauc
uccuaaggcuaaauacucucuagugaccgauagugaaccaguaccgugag
ggaaaggugaaaagcaccccggaaggggagugaaauagaaccugaaaccg
ugugcuuacaaguagucagagcccguuaaugggugauggcgugccuuuug
uagaaugaaccggcgaguuacgauuugaugcaagguuaagcaguaaaugu
ggagccguagcgaaagcgagucugaauagggcguuuaguauuuggucgua
gacccgaaaccaggugaucuacccuuggucagguugaaguucagugaaug
gaggaccgaaccgacuuacguugaaaagugagcggaugaacugaggguag
cggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauagc
uuuagggcuagccucaagugaugauuauuggagguagagcacuguuugga
cgaggccgaauucagacaaacuccgaaugccaauuaauuuaacuugggag
ucagaacaugggugauaagguccguguucgaaagggaaacagcccagacc
accagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguug
cccagacaacuaguagucgagugacacugcgccgaaaauguaccggggcu
aaacauauuaccgaagcugugauuguccuuuggacaaugguaggagagcg
uucuaagggcguugaagcaugaucguaaggacauguggagcgcuuagaag
ugagaaugccggugugaguagcgaaagacgggugagaaucccguccaccg
auugacuaagguuuccagaggaaggcucguccgcucuggguuagucgggu
ccuaagcugaggccgacaggcguaggcgauggauaacagguugauauucc
uguaccaccuauaaucgaucgauggggggacgcaguaggauaggcgaagc
gugcgauuggauugcacgucuaagcaguaaggcugaguaggcugagcugu
gauggggagaagacucuucgagucguugauuucacacugccgagaaaagc
cucuagauagaaaauaggugcccguaccgcaaaccgacacagguagucaa
gaugagaauucuaaggugagcgagcgaacucucguuaaggaacucggcaa
aaugaccccguaacuucgggagaaggggugcucuuuaggguuaacgccca
gaagagccgcagugaauaggcccaagcgacuguuuaucaaaaacacaggu
cucugcuaaaccguaaggugauguauaggggcugacgccugcccggugcu
ggaagguuaagaggagugguuagcuucugcgaagcuacgaaucgaagccc
caguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuu
gucggguaaguuccgacccgcacgaaaggcguaacgauuugggcacuguc
ucaacgagagacucggugaaaucauaguaccugugaagaugcagguuacc
cgcgacaggacggaaagaccccguggagcuuuacuguagccugauauuga
aauucggcacagcuagcuguguuggcuuucuaacccgcaccacuuaucgu
ggugggagacagugucaagcgggcaguuugacuggggcggucgccuccua
aaagguaacggaggcgcucaaagguucccuagaaugguuggaaaucauuc
auagaguguaaaggcauaagggagcuugacugcgagaccuacaagucgag
cagggucgaaagacggacuuagugauccggugguuccgcauggaagggcc
aucgcucaacggauaaaagcuaccccggggauaacaggcuuaucuccccc
aagaguucacaucgacggggagguuuggcaccucgaugucggcucaucgc
auccuggggcuguagucggucccaaggguugggcuguucgcccauuaaag
cgguacgcgagcuggguucagaacgucgugagacaguucggucccuaucc
gucgugggcguaggaaauuugagaggagcuguccuuaguacgggaccggg
auggacauaccucugguguaccaguugucgugccaacggcauagcugggu
agcuauguguggacgggauaagugcugaaagcaucuaagcaugaagcccc
ccucaagaugagauuucccaacuucgguuauaagaucccucaaagaugau
gagguuaauagguucgagguggaagcauggugacauguggagcugacgaa
uacuaaucgaucgaagacuuaau
<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<.....
.<<<<<<.....((.>>>.....<<<...<..<<<)).....>>>.....
>...>>>...>>>....<<<....>>>.....................<<
.................>>.>>.....<.<<......<......>.....
.>>.>............<.....>...<<<<<......<<.....>>...
..>>>>>..(((....<.<..<<<...>>>.>.>.......<<<<<<...
...................<....<<<...<<<<<......>>>>>((..
....<<<.....))>>>...>>>......>..............>>..>>
>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>
>>>>..)))......]].>>>>>>>.]]...............<<....>
>....]].........<<<<....>>>>..................>>>>
>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<....
....>.>.<<.<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>
...>>>...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>
..<......<<<<<<.....<<<<<<<<<..<<<....<<<<...>>>>.
....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>..
.<<<.....>>>......>>>>>>........>..<.<.<......<<<<
<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<<.
...........>>>>>>>..>>.>.....>>>>.>>>>>..>>>>>>>.>
>..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>....<
<<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<<..
.......................>>.>>>>.>>...........)))...
..>>>>>>.>>>...>>>>>>..<...<....>...>......>.>.><.
<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>.
.>.....>>>.>><......<<....<<<<<<.......>>>>>><<<<.
...<<<<<.<<...<<<..<....<.....>...>.>>>....((<<<<<
<<.<.<<<...<<<....>>>...>>>..>>>>..<<<<<........>>
>>>))<<<<<<............<<<<.....<<<<..............
..........................<...<<.........>>...>...
...........<....>..................>>>>..........>
>>>...........>>>>>>>>>>..>>.....<<......>>>>>>>.<
<<.......>>>..>>>>..<<<<....<<<<<<<<.<<.........<.
....<<<<<....<<..>>.....>>>>><<<<<<<...<.......>..
>>>>>>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<
<<..<<<...<......<<<...<....>...>.>>......>...>>>>
>>>>..>>>>>...........................<...........
<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..>..>
>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<
<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<.<<<<<<.<<
<<.<<<<<.<<<<..>>>>.>>>>>.>>>>....<<.<<<<<<.....>>
>>>>>>.....>>>>>>.>>..>>>>>..<<<<.....>>>><<<<<<..
.........>>>>>>..<<...<<<<<<<..<<...............>>
.....<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>
>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>
>>>>.............>>>>..]]>>>>.......<<<<...<<<<<<.
..<<.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<
..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))
>>>>>>>>.....<<<<<....<<<<..<.....................
..>..<<<<<...<<<<...<<<<<<<<<<......>>>>>..>>>>>..
.>>>>.>>>>>...<<<....<<<<<...........>>>>>....>.>>
>>>>........>>>>>................<<<<<<<<.........
>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>
>.>>>...>>>>....>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7asp Staphylococcus aureus 50S after 30 minutes incubation a 37C
Resolution2.86 Å
Binding residue
(original residue number in PDB)
K5 K15 M41 K43 H44 H64 S66 R80 K90
Binding residue
(residue number reindexed from 1)
K4 K14 M40 K42 H43 H63 S65 R79 K89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7asp, PDBe:7asp, PDBj:7asp
PDBsum7asp
PubMed
UniProtW8TRD5

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