Structure of PDB 6wkr Chain S Binding Site BS01

Receptor Information
>6wkr Chain S (length=96) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASR
LAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>6wkr Chain H (length=314) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caggatgtatatatctgagacgtgcctggagactagggagtaatcccctt
ggcggtttaaacgcgggggacagcgcgtacgtgcgttttagcggtgctag
agctgtctacgaccaattgagcggcctgggcaccgggattctccagccgc
cggcagcgctgccggcggctggagaatcccggtgccgaggccgctcaatt
ggtcgtagacagctctagcaccgcttaaacgcacgtacgcgctgtccccc
gcgtttaaaccgccaaggggattactccctagtctccaggcacgtctcag
atatatacatcctg
Receptor-Ligand Complex Structure
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PDB6wkr JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R27 T29 R30 I36 R83 S84 T85
Binding residue
(residue number reindexed from 1)		R1 T3 R4 I10 R57 S58 T59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6wkr, PDBe:6wkr, PDBj:6wkr
PDBsum6wkr
PubMed33479123
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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