Structure of PDB 6gej Chain S Binding Site BS01

Receptor Information
>6gej Chain S (length=208) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKALVEEIDKKTYNPDIYFTSLSRPVKRINYSLADLEARLYTRYTQQEIL
QSDRRFMELNTENFSDLPNVPTLLSDLTGVPRDRIESTTKPIWVLKPETL
REIQLSYKSTKLPKPKRKNTNRIVALKKVLSSKRNLHSFLDSALLNLMDK
NVIYHNVYNKRYFKVLPLITTCSICGGYDSISSCVNCGNKICSVSCFKLH
NETRCRNR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6gej Chain S Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6gej Structure and dynamics of the yeast SWR1-nucleosome complex.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
C244 C247 C268
Binding residue
(residue number reindexed from 1)
C172 C175 C196
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031491 nucleosome binding
GO:0046872 metal ion binding
Biological Process
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0006623 protein targeting to vacuole
Cellular Component
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gej, PDBe:6gej, PDBj:6gej
PDBsum6gej
PubMed30309918
UniProtQ03433|VPS71_YEAST Vacuolar protein sorting-associated protein 71 (Gene Name=VPS71)

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