Structure of PDB 4wfb Chain S Binding Site BS01

Receptor Information
>4wfb Chain S (length=157) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVI
REVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTV
EVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPNINDSLTVADVKVT
GDFKIEN
Ligand information
>4wfb Chain Y (length=114) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucuggugacuauagcaaggaggucacaccuguucccaugccgaacacaga
aguuaaggucuuuagcgacgaugguagccaacuuacguuccgcuagagua
gaacguugccaggc
.<<.<..<.....<<<<<<<......<<<<<...............>>>.
.>>.....>>>>>.>><.........<.<............>.>......
...>..>..>.>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4wfb Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Resolution3.43 Å
Binding residue
(original residue number in PDB)
D17 L18 R22 V30 Y32 N38 Q78 H88
Binding residue
(residue number reindexed from 1)
D15 L16 R20 V28 Y30 N36 Q76 H86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4wfb, PDBe:4wfb, PDBj:4wfb
PDBsum4wfb
PubMed26464510
UniProtQ2G0S0

[Back to BioLiP]