Structure of PDB 4uuv Chain S Binding Site BS01

Receptor Information
>4uuv Chain S (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPA
MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD
Ligand information
Receptor-Ligand Complex Structure
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PDB4uuv Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y392 R397 R400 K410 R415 Y416
Binding residue
(residue number reindexed from 1)		Y53 R58 R61 K71 R76 Y77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4uuv, PDBe:4uuv, PDBj:4uuv
PDBsum4uuv
PubMed25866208
UniProtP43268|ETV4_HUMAN ETS translocation variant 4 (Gene Name=ETV4)

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