Structure of PDB 4ji7 Chain S Binding Site BS01

Receptor Information
>4ji7 Chain S (length=80) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAV
YNGKQHVPVYITENMVGHKLGEFAPTRTYR
Ligand information
>4ji7 Chain A (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaag
acaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcgga
cgggugaguaacgcgugggugaccuacccggaagagggggacaacccggg
gaaacucgggcuaaucccccauguggacccgccccuugggguguguccaa
agggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggug
ggguaauggcccaccaaggcgacgacggguagccggucugagaggauggc
cggccacaggggcacugagacacgggccccacuccuacgggaggcagcag
uuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuugg
aggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccccc
gacgaggggacugacgguaccgggguaauagcgccggccaacuccgugcc
agcagccgcgguaauacggagggcgcgagcguuacccggauucacugggc
guaaagggcguguaggcggccuggggcgucccaugugaaagaccacggcu
caaccgugggggagcgugggauacgcucaggcuagacggugggagagggu
gguggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgc
cgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaag
cguggggagcaaaccggauuagauacccggguaguccacgcccuaaacga
ugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagc
gcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacg
ggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaa
gaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugggg
ugccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcu
cgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccg
uuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaaag
cgggaggaaggaggggacgacgucuggucagcauggcccuuacggccugg
gcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacg
gggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacc
cgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcg
gugaauacguucccgggccuuguacacaccgcccgucacgccaugggagc
gggcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagg
gcccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcg
gcuggauccuuucu
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<
<<.<<<..<<<..<<.<<<<<<<<<.......>>>>>>>>>.>>>>>...
...<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<.
.....>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>.
.<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>>
>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>....<<<<<........<<<<
.....>>>>..........>>>>>......<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<..
...>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>......
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<
<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<.<......<<........>>..
........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>.
................>>>>>>>>.<<<.<<<..<<<<<<.......<<<
<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<
<<<<...<...<<<.....>>>>.....>>>>>>>.....<<<<<....>
>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>>
...>..>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>
>>..>>....>>>.....>>>>>>>......<....<<<<<<<.......
.>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<
<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>
>>>>>>..>>.>>>>>..>.>>...>.....<<<<<<<<<....>>>>>>
>>>...........
Receptor-Ligand Complex Structure
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PDB4ji7 The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
P2 R3 S4 L5 K6 F10 H14 K18 W34 R36 R37 Y52 G54 K55 K70 G72 T77 R78 T79 Y80 R81
Binding residue
(residue number reindexed from 1)
P1 R2 S3 L4 K5 F9 H13 K17 W33 R35 R36 Y51 G53 K54 K69 G71 T76 R77 T78 Y79 R80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4ji7, PDBe:4ji7, PDBj:4ji7
PDBsum4ji7
PubMed24152548
UniProtQ5SHP2|RS19_THET8 Small ribosomal subunit protein uS19 (Gene Name=rpsS)

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