Structure of PDB 3bgo Chain S Binding Site BS01

Receptor Information
>3bgo Chain S (length=263) Species: 1390 (Bacillus amyloliquefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSYGVAQIKAPALHSQGYTGSNVKVAVLASGIDSSHPDLNVAGGASFVPS
ETNPFQDNNSHGTHVAGTVLAVAPSASLYAVKVLGADGSGQASWIINGIE
WAIANNMDVINMSLGSPSGSAALKAAVDKAVASGVVVVAAAGNSGTSGSS
STVSYPAKYPSVIAVGAVDSSNQRAPFSSVGPELDVMAPGVSICSTLPGG
KYGALSGTAMASPHVAGAAALILSKHPNWTNTQVRSSLENTATKLGDSFY
YGKGLINVEAAAQ
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain3bgo Chain S Residue 277 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3bgo Structure of a switchable subtilisin complexed with a substrate and with the activator azide.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		L31 A32 H64 N123 S125
Binding residue
(residue number reindexed from 1)		L28 A29 H61 N111 S113
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) A221
Catalytic site (residue number reindexed from 1) A209
Enzyme Commision number 3.4.21.62: subtilisin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3bgo, PDBe:3bgo, PDBj:3bgo
PDBsum3bgo
PubMed19761257
UniProtP00782|SUBT_BACAM Subtilisin BPN' (Gene Name=apr)

[Back to BioLiP]