Structure of PDB 2jkr Chain S Binding Site BS01

Receptor Information
>2jkr Chain S (length=142) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFV
EFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCE
LDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2jkr A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Resolution2.98 Å
Binding residue
(original residue number in PDB)		N9 R10 Y62 V88 N97 V98 C99 E100 L101
Binding residue
(residue number reindexed from 1)		N9 R10 Y62 V88 N97 V98 C99 E100 L101
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0035615 clathrin adaptor activity
Biological Process
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0048488 synaptic vesicle endocytosis
GO:0072583 clathrin-dependent endocytosis
GO:0098884 postsynaptic neurotransmitter receptor internalization
Cellular Component
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0009898 cytoplasmic side of plasma membrane
GO:0030117 membrane coat
GO:0030122 AP-2 adaptor complex
GO:0045202 synapse
GO:0071944 cell periphery
GO:0098793 presynapse
GO:0098794 postsynapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2jkr, PDBe:2jkr, PDBj:2jkr
PDBsum2jkr
PubMed19140243
UniProtP62743|AP2S1_MOUSE AP-2 complex subunit sigma (Gene Name=Ap2s1)

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