Structure of PDB 1esv Chain S Binding Site BS01

Receptor Information
>1esv Chain S (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTCLYGDFFTGDAYVILKTV
QLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQG
FESATFLGYFKSGLKYKKGGVASGF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1esv Chain S Residue 390 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1esv Latrunculin alters the actin-monomer subunit interface to prevent polymerization.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D85 G90 A92
Binding residue
(residue number reindexed from 1)		D85 G90 A92
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:1esv, PDBe:1esv, PDBj:1esv
PDBsum1esv
PubMed10854330
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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