Structure of PDB 7qvp Chain Rf Binding Site BS01

Receptor Information
>7qvp Chain Rf (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TALQEVLKTALIHDGLARGIREAAKAQAHLCVLASNCDEPMYVKLVEALC
AEKVDDNKKLWVGLVVGCSCVVVKDYGK
Ligand information
>7qvp Chain S3 (length=1705) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuugggggggaugcg
ugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgcccg
uggcggcgacgacccauucgaacgucugcccuaucaacuuucgaugguag
ucgccgugccuaccauggugaccacgggugacggggaaucaggguucgau
uccggagagggagccugagaaacggcuaccacauccaaggaaggcagcag
gcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaca
auacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauc
cuuuaacgaggauccauuggagggcaagucuggugccagcagccgcggua
auuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgu
aguuggaucuugggagcgggcgggcgguccgccgcgaggcgagccaccgc
ccguccccgccgcguuuacuuugaaaaaauuagaguguucaaagcaggcc
cccgccuggauaccgcagcuaggaauaauggaauaggaccgcgguucuau
uuuuuuucggaacugaggccaugauuaagagggacggccgggggcauucg
uauugcgccgcuagaggugaaauucuuggaccggcgcaagacggaccaga
gcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaagucgga
gguucgaagacgaucagauaccgucguaguuccgaccauaaacgaugccg
accggcgaugcggcggcguuauucccaugacccgccgggcagcuuccggg
aaaccaaagucuuuggguuccggggggaguaugguugcaaagcugaaacu
uaaaggaauugacggaagggcaccaccaggaguggagccugcggcuuaau
uugacucaacacgggaaaccucacccggcccggacacggacaggauugac
agauugauagcucuuucucgauuccgugggugguggugcauggccguucu
uaguugguggagcgauuugucugguuaauuccgauaacgaacgagacucu
ggcaugcuaacuaguuacgcgaccccgcggucggcgucaacuucuuagag
ggacaaguggcguucagccacccgagauugagcaauaacaggucugugau
gcccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcgu
gugccuacccuacgccggcaggcgcggguaacccguugaaccccauucgu
gauggggaucggggauugcaauuauuccccaugaacgaggaauucccagu
aagugcgggucauaagcuugcguugauuaagucccugcccuuuguacaca
ccgcccgucgcuacuaccgauuggaugguuuagugaggcccucggaucgg
ccccgccggggugcggagcgcugagaagacggucgaacuugacuaucuag
aggaaguaaaagucguaacaagguuuccguaggugaaccugcggaaggau
cauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<.........<<.....<<.<<<....
.>>>.>>......>>.........<<<<...<<<<.....>>>>...>>>
><<..<<<<<...<......>..>>>>>......>>...<<<<.<<<<..
.>>>>>>>>..>.>>>...>>..>.>>>.<<<....<<<....<<<<<<<
.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>...
.>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>
>>.........<<<....<<<<...>>>>..>>>..>...>>.>....<<
.<<<<<<............>>.>>>>..>>......<<..<.........
..>..>>.........<<<<<((......<<<<.....<<..))>>....
...>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<..
.<<<.<<..........<<<<<<<<<<<.<<<<....>>>>>....>>>>
>>>>>>.........<<<<<<.<.......<<...<.......>.<<<<.
...>>>>...>>......>.>>>..>>>........<.<<.<<.<<<<..
........>>>>.>>.>>.>....>>....<<<<<<..<...<<<<..<<
..<<<<<<<<...<<<......>>>......>>>>>>>>..>>.......
<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<<<<
<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<.
<<.<<<..<.<<<<<<.<<<<<....>>>>>>>>>>>.>..>>>...<<.
.))>>...>>.....>>>.>.>.<<<......<<<......>>>....>>
>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<.....
.<<........>>..........<<<<<......<<<<<<.......<<.
<<<........>>>.>>.....>>>>>>.<.<<.<<<..<<.<<<<<<..
..<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<.
..<...<<<<..<<<<<<<<<<<<....>>>>.>>>>.>>>>..>>>>..
>.....<<<<<.....>>>>>........>>>....>>>.>>>.....>>
>>>>>>......>>>>>...>>.>>>>.>>>.....<<.<<<........
<.......<<<.<<<<....>>>>.>>>....>.........>>>.>>..
..........<<<<<..........>>>>>...........>>>>>....
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<
<...<<......>>.....>>>>>...>>.>>>>..>>>.>>>>>>>>..
.>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>....
.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qvp A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
R33 G34 N82 L91 V104 C106 S107
Binding residue
(residue number reindexed from 1)
R18 G19 N57 L64 V66 C68 S69
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7qvp, PDBe:7qvp, PDBj:7qvp
PDBsum7qvp
PubMed36302773
UniProtA0A671DUR2

[Back to BioLiP]