Structure of PDB 6lqu Chain RY Binding Site BS01

Receptor Information

>6lqu Chain RY (length=37) Species: 559292 (Saccharomyces cerevisiae S288C)

KGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAG

Ligand information

>6lqu Chain SA (length=1242)

aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcaggcucguaguug
aacuuagggacggucgggggcaucaguauucaauugucagaggugaaauu
cuuggauuuauugaagacuaacuacugcgaaagcauuugccaaggacguu
uucauuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccgu
cguagucuuaacuggggggaguauggucgcaaggcugaaacuuaaaggaa
uugacggaagggcaccaccaggaguggagccugcggcucaacacggggaa
acucaccagguccagacacaauaaggauugacauucuugauuuugugggu
gguggugcauugaugcccuuguucugggccacgcgcgcuacacugacgga
gccagcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuc
cgucgugcuggggauauucaacgaggaauuccuaguaagcgcaagucauc
agcuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuag
uaccgauugaauggcuuagugaggccucaggaucugcuuagagaaggggg
caacuccaucucagagcggagaauuuggacaaacuuggucauuuagagga
acuaaaagucguaacaagguuuccguaggugaaccugcggaa

............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<..<.<<...<<<.
......<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>
>......>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.
>>>...>>>...>>.>......<<<<<...<...<<<<.........>>>
>...>>>>>>...>....................<<.........>>...
..<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<<...............
........<<.<....<<<<<........<.....>......>>>>>...
...<<<........>>>...>.>>.......>>>>.>>>.....<<<<<<
<............<<<..<<<<....>>>>..>>>............>>>
>>>>.......................>>>>>>....<<<<<<<<.....
..>>>>>>>>......>>...>>>>>>>............>>>>>..<<<
..<<....<.<<<..<.<<<..<.<<......<<<<<<<.<<<<.<<<<.
...>>>>.>>>>.>>>>>>>......>>.>..>>>.>..>>>>....>>.
.>>>................<<<<<<<<<....>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6lqu Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): G461 R462
• Binding residue (residue number reindexed from 1): G2 R3

Gene Ontology

Molecular Function

• GO:0003674 molecular_function
• GO:0005515 protein binding

Biological Process

• GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006364 rRNA processing
• GO:0015031 protein transport
• GO:0016192 vesicle-mediated transport

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0030686 90S preribosome
• GO:0032040 small-subunit processome

External links

• PDB: RCSB:6lqu, PDBe:6lqu, PDBj:6lqu
• PDBsum: 6lqu
• PubMed: 32943522
• UniProt: Q06631|BFR2_YEAST Protein BFR2 (Gene Name=BFR2)