Structure of PDB 7qvp Chain RT Binding Site BS01 |
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| >7qvp Chain S3 (length=1705)
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uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau
ucuagagcuaauacaugccgacgggcgcugacccccuugggggggaugcg
ugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgcccg
uggcggcgacgacccauucgaacgucugcccuaucaacuuucgaugguag
ucgccgugccuaccauggugaccacgggugacggggaaucaggguucgau
uccggagagggagccugagaaacggcuaccacauccaaggaaggcagcag
gcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaca
auacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauc
cuuuaacgaggauccauuggagggcaagucuggugccagcagccgcggua
auuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgu
aguuggaucuugggagcgggcgggcgguccgccgcgaggcgagccaccgc
ccguccccgccgcguuuacuuugaaaaaauuagaguguucaaagcaggcc
cccgccuggauaccgcagcuaggaauaauggaauaggaccgcgguucuau
uuuuuuucggaacugaggccaugauuaagagggacggccgggggcauucg
uauugcgccgcuagaggugaaauucuuggaccggcgcaagacggaccaga
gcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaagucgga
gguucgaagacgaucagauaccgucguaguuccgaccauaaacgaugccg
accggcgaugcggcggcguuauucccaugacccgccgggcagcuuccggg
aaaccaaagucuuuggguuccggggggaguaugguugcaaagcugaaacu
uaaaggaauugacggaagggcaccaccaggaguggagccugcggcuuaau
uugacucaacacgggaaaccucacccggcccggacacggacaggauugac
agauugauagcucuuucucgauuccgugggugguggugcauggccguucu
uaguugguggagcgauuugucugguuaauuccgauaacgaacgagacucu
ggcaugcuaacuaguuacgcgaccccgcggucggcgucaacuucuuagag
ggacaaguggcguucagccacccgagauugagcaauaacaggucugugau
gcccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcgu
gugccuacccuacgccggcaggcgcggguaacccguugaaccccauucgu
gauggggaucggggauugcaauuauuccccaugaacgaggaauucccagu
aagugcgggucauaagcuugcguugauuaagucccugcccuuuguacaca
ccgcccgucgcuacuaccgauuggaugguuuagugaggcccucggaucgg
ccccgccggggugcggagcgcugagaagacggucgaacuugacuaucuag
aggaaguaaaagucguaacaagguuuccguaggugaaccugcggaaggau
cauua |
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<.........<<.....<<.<<<....
.>>>.>>......>>.........<<<<...<<<<.....>>>>...>>>
><<..<<<<<...<......>..>>>>>......>>...<<<<.<<<<..
.>>>>>>>>..>.>>>...>>..>.>>>.<<<....<<<....<<<<<<<
.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>...
.>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>
>>.........<<<....<<<<...>>>>..>>>..>...>>.>....<<
.<<<<<<............>>.>>>>..>>......<<..<.........
..>..>>.........<<<<<((......<<<<.....<<..))>>....
...>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<..
.<<<.<<..........<<<<<<<<<<<.<<<<....>>>>>....>>>>
>>>>>>.........<<<<<<.<.......<<...<.......>.<<<<.
...>>>>...>>......>.>>>..>>>........<.<<.<<.<<<<..
........>>>>.>>.>>.>....>>....<<<<<<..<...<<<<..<<
..<<<<<<<<...<<<......>>>......>>>>>>>>..>>.......
<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<<<<
<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<.
<<.<<<..<.<<<<<<.<<<<<....>>>>>>>>>>>.>..>>>...<<.
.))>>...>>.....>>>.>.>.<<<......<<<......>>>....>>
>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<.....
.<<........>>..........<<<<<......<<<<<<.......<<.
<<<........>>>.>>.....>>>>>>.<.<<.<<<..<<.<<<<<<..
..<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<.
..<...<<<<..<<<<<<<<<<<<....>>>>.>>>>.>>>>..>>>>..
>.....<<<<<.....>>>>>........>>>....>>>.>>>.....>>
>>>>>>......>>>>>...>>.>>>>.>>>.....<<.<<<........
<.......<<<.<<<<....>>>>.>>>....>.........>>>.>>..
..........<<<<<..........>>>>>...........>>>>>....
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<
<...<<......>>.....>>>>>...>>.>>>>..>>>.>>>>>>>>..
.>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>....
..... |
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| PDB | 7qvp A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | P2 V4 K7 Q12 V15 W33 V37 K41 K43 E44 A46 P47 Y48 R56 S59 R62 H63 R67 G71 G73 S74 K77 I78 R82 R84 G86 V87 M88 P89 H91 F92 S96 K97 S98 R101 R102 G119 G120 R121 P125 Q128 R129 D132 R133 |
Binding residue
(residue number reindexed from 1) | P1 V3 K6 Q11 V14 W32 V36 K40 K42 E43 A45 P46 Y47 R55 S58 R61 H62 R66 G70 G72 S73 K76 I77 R81 R83 G85 V86 M87 P88 H90 F91 S95 K96 S97 R100 R101 G118 G119 R120 P124 Q127 R128 D131 R132 |
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| Enzyme Commision number |
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