Structure of PDB 6lqq Chain RQ Binding Site BS01

Receptor Information
>6lqq Chain RQ (length=226) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDDRQVIENANLLKGKSSTYEVPLPQRIQQRHDRKAAYEISRQEVSKWND
IVQQNRRADHLIFPLNKPTEHNHASAFTRTQDVPQTELQEKVDQVLQESN
LANPEKDSKFEELPEEMRKRTTEMRLMRELMFREERKARRLKKIKSKTYR
KILQNVIINEKVNKKNLKYQSSAVPFPFENREQYERSLRMPIGQEWTSRA
SHQELIKPRIMTKPGQVIDPLKAPFK
Ligand information
>6lqq Chain 5A (length=375) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcaguugaagacaaguggcuugucguucguuaaaauggccucg
ucaaacggugguacagcguguuuaauugacauggguugauaaccugaaca
gucucaucguggccauuggugagcagcgaaggauuugguggauuacuagc
uaauagcaaucuauuucaaagaauucaaacuugggggaaugccuuguuga
auagccggucgcaagacugugauucuucaaguguaaccuccucucuauca
aacguaccgguaucuguuuggugggaaacucaaagagugcuaugguaugg
ugacggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcau
uuccggcagcagagauuucagcugu
<<<....>>>...<<<<<<<<<<.>>>>>>>.>>>..............<
<<<<<<<.<<...>>.>>>......>>>>>..<<<<<<.>>>>>>.....
..<<<<<<<<<..>>>.>>>>>>.........................<<
<...>>>.........................<<<<<..<<<<<<<..<<
<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>>....<<<<<
<<<<<<<..>>>.>.>>>>>>>>...........................
...<<<<.<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>.
.>>>><<<<<.<<<..>>>.>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqq Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		E320 H321 N322 H323 S325 D332 M373 E833 K834 V835 K838 R872 Q876 K880 M884 K886
Binding residue
(residue number reindexed from 1)		E70 H71 N72 H73 S75 D82 M117 E160 K161 V162 K165 R199 Q203 K207 M211 K213
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqq, PDBe:6lqq, PDBj:6lqq
PDBsum6lqq
PubMed32943522
UniProtQ04500|UTP14_YEAST U3 small nucleolar RNA-associated protein 14 (Gene Name=UTP14)

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