Structure of PDB 7d5s Chain RN Binding Site BS01

Receptor Information
>7d5s Chain RN (length=607) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGSQLKNLKAALKARGYDREEKKKAIAEIREEFNPFEIKAARNKRIAVGK
PGISKQIGEEQRKRAFEARKMMKNKRGGVIDKRPQRKKTKAEVMKEVIAK
SKFYKQERQKAQGIMEDQIDNLDDNFEDVMSELMMTDLDKEYDIKVKELQ
LDKRAAPSDRTKTEEEKNAEAEEKKRELEQQRLDRMNGRTHDALLDQVKK
LDLDDHPKIVKNIIKAYQPKLAEGNKEKLGKFTAVLLRHIIFLSNQNYLK
NVQSFKRTQNALISILKSLSEKYNRELSEECRDYINEMQARYKKNHFDAL
SNGDLVFFSIIGILFSTSDQYHLVITPALILMSQFLEQIKFNSLKRIAFG
AVLVRIVSQYQRISKRYIPEVVYFFQKILLTFIVEPLDFENIRLDSYELG
LPLDVDFTKKRSTIIPLHTLSTMDTEAHPVDQCVSVLLNVMESLDATIST
VWKSLPAFNEIILPIQQLLSAYTSKYSDFEKPRNILNKVEKLTKFTEHIP
LALQNHKPVSIPTHAPKYEENFNPDKKSYDPDRTRSEINKMKAQLKKERK
FTMKEIRKDAKFEARQRIEEKNKESSDYHAKMAHIVNTINTEEGAEKNKY
ERERKLR
Ligand information
>7d5s Chain 3A (length=175) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccagugagaaauugccguugcuauggcgcgaugaucacccaugggu
ggguacaaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<..<.........<<<<......>>>>.......>.<<<<..>>>>
.>>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7d5s Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2)
Resolution4.6 Å
Binding residue
(original residue number in PDB)		T790 A794 N797
Binding residue
(residue number reindexed from 1)		T591 A595 N598
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0030692 Noc4p-Nop14p complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7d5s, PDBe:7d5s, PDBj:7d5s
PDBsum7d5s
PubMed
UniProtQ99207|NOP14_YEAST Nucleolar complex protein 14 (Gene Name=NOP14)

[Back to BioLiP]