Structure of PDB 7d4i Chain RJ Binding Site BS01

Receptor Information
>7d4i Chain RJ (length=738) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMQRSSDVNERKLHVPMVDRTPEDDPPPFIVAVVGPPGTGKTTLIRSLVR
RMTKSTLNDIQGPITVVSGKHRRLTFLECPADDLNAMIDIAKIADLVLLL
IDGNFGFEMETMEFLNIAQHHGMPRVLGVATHLDLFKSQSTLRASKKRLK
HRFWTEVYQGAKLFYLSGVINGRYPDREILNLSRFISVMKFRPLKWRNEH
PYMLADRFTDLTHPELIETQGLQIDRKVAIYGYLHGTPLPSAPGTRVHIA
GVGDFSVAQIEKLPDPCPTPFYQQKLLIYAPMSNIGKLIYMDNISPEECI
RRWRDLEKFVPYFDTFEKLAKKWKSVDAIKERFLTWYELQKAKISKQLEI
NNIEYQEMTPEQRQRIEGFKAGSYVRIVFEKVPMEFVKNFNPKFPIVMGG
LLPTEIKFGIVKARLRRHRWHKKILKTNDPLVLSLGWRRFQTLPIYTTTD
SRTRTRMLKYTPEHTYCNAAFYGPLCSPNTPFCGVQIVANSDTGNGFRIA
ATGIVEEIDVNIEIVKKLKLVGFPYKIFKNTAFIKDMFSSAMEVARFEGA
QIKTVSGIRGEIKRALSKPEGHYRAAFEDKILMSDIVILRSWYPVRVKKF
YNPVTSLLLKEKTEWKGLRLTGQIRAAMNLETPSNPDSAYHKIERVERHF
NGLKVPKAVQKELPFKSQIAKRAVVLGGDEKKARSFIQKVLTISKAKDSK
RKEQKASQRKERLKKLAKMEEEKSQRDKEKKKEYFAQN
Ligand information
>7d4i Chain 3A (length=216) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucgacguacuucaaggaucauuucuauaggaaucgucacucuuugacucu
ucccaacuugguugaugagucccauaaccuuuguaccccagagugagaaa
gcuuggccgaauccucgguucggccacuauugccguugcauuuuauggcg
cgaugaucuugacccauccuaucuucgaagauaggauggguggguacaaa
uggcagucugacaagu
..................................................
.....<<<<<.................<<<<<<<<<<<....<...<...
<..<<<<<<<<<<...>>>>>>>>>>.>...<<<<..........>>>>.
>......>..<..<<<<<<<<<<<<..>>>>>>>>>>>>.>>>>>>>>>>
.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d4i Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1
Resolution4.0 Å
Binding residue
(original residue number in PDB)
K1154 K1157 Y1160 F1161
Binding residue
(residue number reindexed from 1)
K728 K731 Y734 F735
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:2000232 regulation of rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0032040 small-subunit processome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7d4i, PDBe:7d4i, PDBj:7d4i
PDBsum7d4i
PubMed
UniProtQ08965|BMS1_YEAST Ribosome biogenesis protein BMS1 (Gene Name=BMS1)

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